Get Involved
Study of Kidney Tumors in Younger Patients
Study Purpose
This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Recruitment Criteria
|
Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
|
Study Type
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Observational |
| Eligible Ages | N/A - 29 Years |
| Gender | All |
Inclusion Criteria:
- - Patients with the first occurrence of any tumor of the kidney identified on CT scan or MRI are eligible for this study; histologic diagnosis is not required prior to enrollment but is required for all patients once on study.
- - Eligible tumors include (but are not limited to): - Nephroblastic tumors.
- - Nephroblastoma (Wilms' tumor) (favorable histology, anaplasia [diffuse, focal]) - Nephrogenic rests and nephroblastomatosis.
- - Cystic nephroma and cystic partially differentiated nephroblastoma.
- - Metanephric tumors (metanephric adenoma, metanephric adenofibroma, metanephric stromal tumor) - Mesoblastic nephroma (cellular, classic, mixed) - Clear cell sarcoma.
- - Rhabdoid tumor (any malignant rhabdoid tumor occurring outside the central nervous system [CNS]) - Renal epithelioid tumors of childhood (papillary renal cell carcinoma, medullary renal cell carcinoma, renal tumors associated with Xp11.2 translocations, oncocytic renal neoplasms after neuroblastoma) - Angiolipoma.
- - Ossifying renal tumor of infancy.
- - Patients with the first occurrence of the following tumors are also eligible: - Extrarenal nephroblastoma or extrarenal neprogenic rests.
- - Malignant rhabdoid tumor occurring anywhere outside the central nervous system.
- - Required specimens, reports, forms, and copies of imaging studies must be available or will become available for submission and the institution must intend on submitting them as described in the protocol procedures.
- - For ALL patients, (with exception of bilateral, bilaterally predisposed, multicentric, or unilateral tumor in solitary kidney planning to enroll without biopsy***), the following submissions are required: - A complete set of recut hematoxylin and eosin (H & E) slides (including from sampled lymph nodes, if patient had upfront nephrectomy) - * Tissue must be from diagnosis, prior to any renal tumor directed chemotherapy or radiation (only exception is for presumed favorable histology Wilms tumor [FHWT] patients discovered to have diffuse anaplastic Wilms tumor [DAWT] at delayed nephrectomy and plan to enroll at delayed nephrectomy) - Representative formalin-fixed paraffin-embedded tissue block or if a block is unavailable, 10 unstained slides from a representative block of tumor, if available.
- - Tissue must be from diagnosis, prior to any renal tumor directed chemotherapy or radiation (only exception is for presumed FHWT patients discovered to have DAWT at delayed nephrectomy and plan to enroll at delayed nephrectomy) - Institutional pathology report, Specimen Transmittal Form, and Pre-Treatment Pathology Checklist.
- - Copies of images and institutional reports of CT and/or MRI abdomen and pelvis, and Pre Treatment Imaging Checklist.
- - Copies of images and institutional report of chest CT for all malignant tumors.
- - Institutional surgical report(s) and Pre-Treatment Surgical Checklist.
- - CRFs: Staging Checklist and Metastatic Disease Form (if metastatic disease is noted on imaging) - Patients with bilateral, bilaterally predisposed, multicentric, or unilateral tumor in solitary kidney planning to enroll without biopsy via imaging only - these patients will not have central review or have a risk assignment issued, but may contribute to specimen banking for future research.
- - Please note: if the above required items are not received within 120 days of study enrollment, the patient will be considered off study.
- - All patients and/or their parents or legal guardians must sign a written informed consent.
Trial Details
|
Trial ID:
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT00898365 |
|
Phase
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
|
|
Lead Sponsor
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
Children's Oncology Group |
|
Principal Investigator
The person who is responsible for the scientific and technical direction of the entire clinical study. |
Elizabeth A Mullen |
| Principal Investigator Affiliation | Children's Oncology Group |
|
Agency Class
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
Other, NIH |
| Overall Status | Recruiting |
| Countries | Australia, Canada, Israel, New Zealand, Puerto Rico, Switzerland, United States |
|
Conditions
The disease, disorder, syndrome, illness, or injury that is being studied. |
Adult Cystic Nephroma, Anaplastic Kidney Wilms Tumor, Angiolipoma, Cellular Congenital Mesoblastic Nephroma, Classic Congenital Mesoblastic Nephroma, Clear Cell Sarcoma of the Kidney, Congenital Mesoblastic Nephroma, Cystic Partially Differentiated Kidney Nephroblastoma, Diffuse Hyperplastic Perilobar Nephroblastomatosis, Extrarenal Rhabdoid Tumor, Kidney Medullary Carcinoma, Kidney Neoplasm, Kidney Oncocytoma, Kidney Wilms Tumor, Metanephric Adenofibroma, Metanephric Adenoma, Metanephric Stromal Tumor, Metanephric Tumor, Mixed Congenital Mesoblastic Nephroma, Ossifying Renal Tumor of Infancy, Papillary Renal Cell Carcinoma, Renal Cell Carcinoma, Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions, Rhabdoid Tumor of the Kidney, Wilms Tumor |
PRIMARY OBJECTIVES:
- I. Classify patients with renal tumors by histological categorization, surgico-pathological stage, presence of metastases, age at diagnosis, tumor weight, and loss of heterozygosity for chromosomes 1p and 16q, to define eligibility for a series of therapeutic studies.
- II. To maintain a biological samples bank to make specimens available to scientists to evaluate additional potential biological prognostic variables and for the conduct of other research by scientists.
- I. To monitor outcome for those patients who are not eligible for a subsequent therapeutic study.
- II. To describe whether the pulmonary tumor burden correlates with outcome in Stage IV patients.
- III. To describe the sensitivity and specificity of abdominal computed tomography (CT) by comparison with surgical and pathologic findings for identification of local tumor spread beyond the renal capsule to adjacent muscle and organs, lymph node involvement at the renal hilum and in the retroperitoneum, preoperative tumor rupture and metastases to the liver.
- IV. To compare the sensitivity and specificity of preoperative abdominal CT and MRI for the identification and differentiation of nephrogenic rests and Wilms tumor in children with multiple renal lesions.
- V. To correlate the method of conception (natural versus assisted reproductive technology) with the development of Wilms tumor.
- VI. To evaluate the frequency of integrase interactor 1 (INI1) mutations in renal and extrarenal malignant rhabdoid tumor of the kidney and to determine the incidence of germline and inherited versus somatic mutations to facilitate clinical correlations on the companion study AREN0321.
Arms
: Ancillary-correlative (renal tumor classification, biology)
Tumor tissue, blood, and urine samples are collected for research studies, including immunohistochemistry. CT scans and MRIs are also performed. Loss of heterozygosity analyses (chromosome 1p and 16q) are performed by extraction of DNA. DNA polymorphisms are assayed by polymerase chain reaction using standard methodology. Leftover specimens are archived for future studies. (LOH and INI1 testing discontinued as of April 2014)
Interventions
Other: - Cytology Specimen Collection Procedure
Correlative studies
Other: - Laboratory Biomarker Analysis
Correlative studies
Contact a Trial Team
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
Status
Recruiting
Address
Children's Hospital of Alabama
Birmingham, Alabama, 35233
Status
Active, not recruiting
Address
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233
Status
Recruiting
Address
USA Health Strada Patient Care Center
Mobile, Alabama, 36604
Status
Recruiting
Address
Providence Alaska Medical Center
Anchorage, Alaska, 99508
Status
Recruiting
Address
Phoenix Childrens Hospital
Phoenix, Arizona, 85016
Status
Recruiting
Address
Banner University Medical Center - Tucson
Tucson, Arizona, 85719
Status
Recruiting
Address
Arkansas Children's Hospital
Little Rock, Arkansas, 72202-3591
Status
Active, not recruiting
Address
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
Status
Recruiting
Address
Kaiser Permanente Downey Medical Center
Downey, California, 90242
Status
Recruiting
Address
City of Hope Comprehensive Cancer Center
Duarte, California, 91010
Status
Recruiting
Address
Loma Linda University Medical Center
Loma Linda, California, 92354
Status
Recruiting
Address
Miller Children's and Women's Hospital Long Beach
Long Beach, California, 90806
Status
Recruiting
Address
Children's Hospital Los Angeles
Los Angeles, California, 90027
Status
Recruiting
Address
Cedars Sinai Medical Center
Los Angeles, California, 90048
Status
Recruiting
Address
Mattel Children's Hospital UCLA
Los Angeles, California, 90095
Status
Recruiting
Address
Valley Children's Hospital
Madera, California, 93636
Status
Recruiting
Address
Children's Hospital and Research Center at Oakland
Oakland, California, 94609-1809
Status
Recruiting
Address
Kaiser Permanente-Oakland
Oakland, California, 94611
Status
Recruiting
Address
Children's Hospital of Orange County
Orange, California, 92868
Status
Recruiting
Address
Lucile Packard Children's Hospital Stanford University
Palo Alto, California, 94304
Status
Recruiting
Address
Sutter Medical Center Sacramento
Sacramento, California, 95816
Status
Recruiting
Address
University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817
Status
Recruiting
Address
Rady Children's Hospital - San Diego
San Diego, California, 92123
Status
Recruiting
Address
Naval Medical Center -San Diego
San Diego, California, 92134
Status
Active, not recruiting
Address
UCSF Medical Center-Parnassus
San Francisco, California, 94143
Status
Recruiting
Address
UCSF Medical Center-Mission Bay
San Francisco, California, 94158
Status
Recruiting
Address
Santa Barbara Cottage Hospital
Santa Barbara, California, 93102
Status
Recruiting
Address
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Torrance, California, 90502
Status
Recruiting
Address
Children's Hospital Colorado
Aurora, Colorado, 80045
Status
Recruiting
Address
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center
Denver, Colorado, 80218
Status
Recruiting
Address
Connecticut Children's Medical Center
Hartford, Connecticut, 06106
Status
Recruiting
Address
Yale University
New Haven, Connecticut, 06520
Status
Recruiting
Address
Alfred I duPont Hospital for Children
Wilmington, Delaware, 19803
Status
Recruiting
Address
MedStar Georgetown University Hospital
Washington, District of Columbia, 20007
Status
Recruiting
Address
Children's National Medical Center
Washington, District of Columbia, 20010
Status
Recruiting
Address
Broward Health Medical Center
Fort Lauderdale, Florida, 33316
Status
Active, not recruiting
Address
Lee Memorial Health System
Fort Myers, Florida, 33901
Status
Recruiting
Address
Golisano Children's Hospital of Southwest Florida
Fort Myers, Florida, 33908
Status
Suspended
Address
University of Florida Health Science Center - Gainesville
Gainesville, Florida, 32610
Status
Recruiting
Address
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida, 33021
Status
Recruiting
Address
Nemours Children's Clinic-Jacksonville
Jacksonville, Florida, 32207
Status
Recruiting
Address
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136
Status
Recruiting
Address
Nicklaus Children's Hospital
Miami, Florida, 33155
Status
Recruiting
Address
Miami Cancer Institute
Miami, Florida, 33176
Status
Recruiting
Address
AdventHealth Orlando
Orlando, Florida, 32803
Status
Recruiting
Address
Arnold Palmer Hospital for Children
Orlando, Florida, 32806
Status
Active, not recruiting
Address
Nemours Children's Clinic - Orlando
Orlando, Florida, 32806
Status
Active, not recruiting
Address
UF Cancer Center at Orlando Health
Orlando, Florida, 32806
Status
Recruiting
Address
Nemours Children's Hospital
Orlando, Florida, 32827
Status
Active, not recruiting
Address
Nemours Children's Clinic - Pensacola
Pensacola, Florida, 32504
Status
Recruiting
Address
Johns Hopkins All Children's Hospital
Saint Petersburg, Florida, 33701
Status
Active, not recruiting
Address
Tampa General Hospital
Tampa, Florida, 33606
Status
Suspended
Address
Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa, Florida, 33607
Status
Recruiting
Address
Saint Mary's Hospital
West Palm Beach, Florida, 33407
Status
Recruiting
Address
Children's Healthcare of Atlanta - Egleston
Atlanta, Georgia, 30322
Status
Recruiting
Address
Augusta University Medical Center
Augusta, Georgia, 30912
Status
Recruiting
Address
Medical Center of Central Georgia
Macon, Georgia, 31201
Status
Recruiting
Address
Memorial Health University Medical Center
Savannah, Georgia, 31404
Status
Active, not recruiting
Address
University of Hawaii Cancer Center
Honolulu, Hawaii, 96813
Status
Recruiting
Address
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826
Status
Active, not recruiting
Address
Tripler Army Medical Center
Honolulu, Hawaii, 96859
Status
Recruiting
Address
Saint Luke's Mountain States Tumor Institute
Boise, Idaho, 83712
Status
Recruiting
Address
Lurie Children's Hospital-Chicago
Chicago, Illinois, 60611
Status
Recruiting
Address
University of Illinois
Chicago, Illinois, 60612
Status
Suspended
Address
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
Status
Suspended
Address
Loyola University Medical Center
Maywood, Illinois, 60153
Status
Recruiting
Address
Advocate Children's Hospital-Oak Lawn
Oak Lawn, Illinois, 60453
Status
Recruiting
Address
Advocate Children's Hospital-Park Ridge
Park Ridge, Illinois, 60068
Status
Active, not recruiting
Address
Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068
Status
Recruiting
Address
Saint Jude Midwest Affiliate
Peoria, Illinois, 61637
Status
Recruiting
Address
Southern Illinois University School of Medicine
Springfield, Illinois, 62702
Status
Suspended
Address
Riley Hospital for Children
Indianapolis, Indiana, 46202
Status
Suspended
Address
Saint Vincent Hospital and Health Care Center
Indianapolis, Indiana, 46260
Status
Recruiting
Address
Blank Children's Hospital
Des Moines, Iowa, 50309
Status
Recruiting
Address
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, 52242
Status
Completed
Address
University of Kansas Cancer Center
Kansas City, Kansas, 66160
Status
Suspended
Address
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536
Status
Recruiting
Address
Norton Children's Hospital
Louisville, Kentucky, 40202
Status
Active, not recruiting
Address
Tulane University Health Sciences Center
New Orleans, Louisiana, 70112
Status
Recruiting
Address
Children's Hospital New Orleans
New Orleans, Louisiana, 70118
Status
Recruiting
Address
Ochsner Medical Center Jefferson
New Orleans, Louisiana, 70121
Status
Recruiting
Address
Eastern Maine Medical Center
Bangor, Maine, 04401
Status
Recruiting
Address
Maine Children's Cancer Program
Scarborough, Maine, 04074
Status
Recruiting
Address
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201
Status
Recruiting
Address
Sinai Hospital of Baltimore
Baltimore, Maryland, 21215
Status
Recruiting
Address
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287
Status
Recruiting
Address
Walter Reed National Military Medical Center
Bethesda, Maryland, 20889-5600
Status
Recruiting
Address
Floating Hospital for Children at Tufts Medical Center
Boston, Massachusetts, 02111
Status
Recruiting
Address
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114
Status
Recruiting
Address
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215
Status
Suspended
Address
Baystate Medical Center
Springfield, Massachusetts, 01199
Status
Recruiting
Address
UMass Memorial Medical Center - University Campus
Worcester, Massachusetts, 01655
Status
Recruiting
Address
C S Mott Children's Hospital
Ann Arbor, Michigan, 48109
Status
Recruiting
Address
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, 48201
Status
Recruiting
Address
Ascension Saint John Hospital
Detroit, Michigan, 48236
Status
Recruiting
Address
Michigan State University Clinical Center
East Lansing, Michigan, 48824-7016
Status
Active, not recruiting
Address
Hurley Medical Center
Flint, Michigan, 48503
Status
Suspended
Address
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan, 49503
Status
Recruiting
Address
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007
Status
Active, not recruiting
Address
Kalamazoo Center for Medical Studies
Kalamazoo, Michigan, 49008
Status
Recruiting
Address
Beaumont Children's Hospital-Royal Oak
Royal Oak, Michigan, 48073
Status
Active, not recruiting
Address
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, 48073
Status
Suspended
Address
Children's Hospitals and Clinics of Minnesota - Minneapolis
Minneapolis, Minnesota, 55404
Status
Recruiting
Address
University of Minnesota/Masonic Cancer Center
Minneapolis, Minnesota, 55455
Status
Recruiting
Address
Mayo Clinic in Rochester
Rochester, Minnesota, 55905
Status
Suspended
Address
University of Mississippi Medical Center
Jackson, Mississippi, 39216
Status
Recruiting
Address
Columbia Regional
Columbia, Missouri, 65201
Status
Recruiting
Address
Children's Mercy Hospitals and Clinics
Kansas City, Missouri, 64108
Status
Recruiting
Address
Cardinal Glennon Children's Medical Center
Saint Louis, Missouri, 63104
Status
Recruiting
Address
Washington University School of Medicine
Saint Louis, Missouri, 63110
Status
Recruiting
Address
Mercy Hospital Saint Louis
Saint Louis, Missouri, 63141
Status
Recruiting
Address
Children's Hospital and Medical Center of Omaha
Omaha, Nebraska, 68114
Status
Recruiting
Address
University of Nebraska Medical Center
Omaha, Nebraska, 68198
Status
Recruiting
Address
University Medical Center of Southern Nevada
Las Vegas, Nevada, 89102
Status
Recruiting
Address
Sunrise Hospital and Medical Center
Las Vegas, Nevada, 89109
Status
Recruiting
Address
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada, 89135
Status
Suspended
Address
Summerlin Hospital Medical Center
Las Vegas, Nevada, 89144
Status
Recruiting
Address
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756
Status
Recruiting
Address
Hackensack University Medical Center
Hackensack, New Jersey, 07601
Status
Active, not recruiting
Address
Saint Barnabas Medical Center
Livingston, New Jersey, 07039
Status
Recruiting
Address
Morristown Medical Center
Morristown, New Jersey, 07960
Status
Recruiting
Address
Saint Peter's University Hospital
New Brunswick, New Jersey, 08901
Status
Recruiting
Address
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital
New Brunswick, New Jersey, 08903
Status
Suspended
Address
Newark Beth Israel Medical Center
Newark, New Jersey, 07112
Status
Recruiting
Address
Saint Joseph's Regional Medical Center
Paterson, New Jersey, 07503
Status
Active, not recruiting
Address
Overlook Hospital
Summit, New Jersey, 07902
Status
Recruiting
Address
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87102
Status
Recruiting
Address
Albany Medical Center
Albany, New York, 12208
Status
Recruiting
Address
Montefiore Medical Center - Moses Campus
Bronx, New York, 10467
Status
Active, not recruiting
Address
Brooklyn Hospital Center
Brooklyn, New York, 11201
Status
Suspended
Address
Roswell Park Cancer Institute
Buffalo, New York, 14263
Status
Recruiting
Address
NYU Winthrop Hospital
Mineola, New York, 11501
Status
Suspended
Address
The Steven and Alexandra Cohen Children's Medical Center of New York
New Hyde Park, New York, 11040
Status
Suspended
Address
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016
Status
Recruiting
Address
Mount Sinai Hospital
New York, New York, 10029
Status
Recruiting
Address
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032
Status
Suspended
Address
Memorial Sloan Kettering Cancer Center
New York, New York, 10065
Status
Suspended
Address
NYP/Weill Cornell Medical Center
New York, New York, 10065
Status
Suspended
Address
University of Rochester
Rochester, New York, 14642
Status
Recruiting
Address
Stony Brook University Medical Center
Stony Brook, New York, 11794
Status
Recruiting
Address
State University of New York Upstate Medical University
Syracuse, New York, 13210
Status
Recruiting
Address
New York Medical College
Valhalla, New York, 10595
Status
Recruiting
Address
Mission Hospital
Asheville, North Carolina, 28801
Status
Recruiting
Address
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599
Status
Recruiting
Address
Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina, 28203
Status
Recruiting
Address
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, 28204
Status
Recruiting
Address
Duke University Medical Center
Durham, North Carolina, 27710
Status
Recruiting
Address
East Carolina University
Greenville, North Carolina, 27834
Status
Recruiting
Address
Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157
Status
Recruiting
Address
Sanford Broadway Medical Center
Fargo, North Dakota, 58122
Status
Recruiting
Address
Children's Hospital Medical Center of Akron
Akron, Ohio, 44308
Status
Recruiting
Address
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229
Status
Recruiting
Address
Rainbow Babies and Childrens Hospital
Cleveland, Ohio, 44106
Status
Recruiting
Address
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
Status
Recruiting
Address
Nationwide Children's Hospital
Columbus, Ohio, 43205
Status
Recruiting
Address
Dayton Children's Hospital
Dayton, Ohio, 45404
Status
Recruiting
Address
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
Toledo, Ohio, 43606
Status
Suspended
Address
Mercy Children's Hospital
Toledo, Ohio, 43608
Status
Recruiting
Address
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
Status
Recruiting
Address
Natalie Warren Bryant Cancer Center at Saint Francis
Tulsa, Oklahoma, 74136
Status
Recruiting
Address
Legacy Emanuel Children's Hospital
Portland, Oregon, 97227
Status
Active, not recruiting
Address
Legacy Emanuel Hospital and Health Center
Portland, Oregon, 97227
Status
Recruiting
Address
Oregon Health and Science University
Portland, Oregon, 97239
Status
Suspended
Address
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, 18103
Status
Suspended
Address
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, 18017
Status
Recruiting
Address
Geisinger Medical Center
Danville, Pennsylvania, 17822
Status
Recruiting
Address
Penn State Children's Hospital
Hershey, Pennsylvania, 17033
Status
Recruiting
Address
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
Status
Recruiting
Address
Saint Christopher's Hospital for Children
Philadelphia, Pennsylvania, 19134
Status
Recruiting
Address
Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15224
Status
Recruiting
Address
Rhode Island Hospital
Providence, Rhode Island, 02903
Status
Recruiting
Address
Medical University of South Carolina
Charleston, South Carolina, 29425
Status
Recruiting
Address
Prisma Health Richland Hospital
Columbia, South Carolina, 29203
Status
Recruiting
Address
BI-LO Charities Children's Cancer Center
Greenville, South Carolina, 29605
Status
Active, not recruiting
Address
Greenville Cancer Treatment Center
Greenville, South Carolina, 29605
Status
Recruiting
Address
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134
Status
Suspended
Address
T C Thompson Children's Hospital
Chattanooga, Tennessee, 37403
Status
Recruiting
Address
East Tennessee Childrens Hospital
Knoxville, Tennessee, 37916
Status
Recruiting
Address
Saint Jude Children's Research Hospital
Memphis, Tennessee, 38105
Status
Recruiting
Address
The Children's Hospital at TriStar Centennial
Nashville, Tennessee, 37203
Status
Recruiting
Address
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, 37232
Status
Recruiting
Address
Texas Tech University Health Sciences Center-Amarillo
Amarillo, Texas, 79106
Status
Recruiting
Address
Dell Children's Medical Center of Central Texas
Austin, Texas, 78723
Status
Recruiting
Address
Driscoll Children's Hospital
Corpus Christi, Texas, 78411
Status
Recruiting
Address
Medical City Dallas Hospital
Dallas, Texas, 75230
Status
Recruiting
Address
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390
Status
Suspended
Address
Brooke Army Medical Center
Fort Sam Houston, Texas, 78234
Status
Recruiting
Address
Cook Children's Medical Center
Fort Worth, Texas, 76104
Status
Recruiting
Address
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, 77030
Status
Recruiting
Address
M D Anderson Cancer Center
Houston, Texas, 77030
Status
Recruiting
Address
Covenant Children's Hospital
Lubbock, Texas, 79410
Status
Recruiting
Address
UMC Cancer Center / UMC Health System
Lubbock, Texas, 79415
Status
Recruiting
Address
Children's Hospital of San Antonio
San Antonio, Texas, 78207
Status
Recruiting
Address
Methodist Children's Hospital of South Texas
San Antonio, Texas, 78229
Status
Recruiting
Address
University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229
Status
Suspended
Address
Scott and White Memorial Hospital
Temple, Texas, 76508
Status
Suspended
Address
Primary Children's Hospital
Salt Lake City, Utah, 84113
Status
Recruiting
Address
University of Vermont and State Agricultural College
Burlington, Vermont, 05405
Status
Recruiting
Address
University of Virginia Cancer Center
Charlottesville, Virginia, 22908
Status
Recruiting
Address
Inova Fairfax Hospital
Falls Church, Virginia, 22042
Status
Recruiting
Address
Children's Hospital of The King's Daughters
Norfolk, Virginia, 23507
Status
Active, not recruiting
Address
Naval Medical Center - Portsmouth
Portsmouth, Virginia, 23708-2197
Status
Recruiting
Address
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298
Status
Recruiting
Address
Carilion Children's
Roanoke, Virginia, 24014
Status
Recruiting
Address
Seattle Children's Hospital
Seattle, Washington, 98105
Status
Recruiting
Address
Providence Sacred Heart Medical Center and Children's Hospital
Spokane, Washington, 99204
Status
Recruiting
Address
Mary Bridge Children's Hospital and Health Center
Tacoma, Washington, 98405
Status
Recruiting
Address
Madigan Army Medical Center
Tacoma, Washington, 98431
Status
Recruiting
Address
West Virginia University Charleston Division
Charleston, West Virginia, 25304
Status
Completed
Address
Cabell-Huntington Hospital
Huntington, West Virginia, 25701
Status
Recruiting
Address
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, 54301
Status
Recruiting
Address
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, 53792
Status
Recruiting
Address
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449
Status
Recruiting
Address
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226
International Sites
Status
Recruiting
Address
John Hunter Children's Hospital
Hunter Regional Mail Centre, New South Wales, 2310
Status
Recruiting
Address
Sydney Children's Hospital
Randwick, New South Wales, 2031
Status
Recruiting
Address
The Children's Hospital at Westmead
Westmead, New South Wales, 2145
Status
Active, not recruiting
Address
Royal Brisbane and Women's Hospital
Herston, Queensland, 4029
Status
Active, not recruiting
Address
Royal Children's Hospital-Brisbane
Herston, Queensland, 4029
Status
Recruiting
Address
Queensland Children's Hospital
South Brisbane, Queensland, 4101
Status
Recruiting
Address
Women's and Children's Hospital-Adelaide
North Adelaide, South Australia, 5006
Status
Suspended
Address
Monash Medical Center-Clayton Campus
Clayton, Victoria, 3168
Status
Suspended
Address
Royal Children's Hospital
Parkville, Victoria, 3052
Status
Active, not recruiting
Address
Princess Margaret Hospital for Children
Perth, Western Australia, 6008
Status
Suspended
Address
Perth Children's Hospital
Perth, Western Australia, 6009
Status
Recruiting
Address
Alberta Children's Hospital
Calgary, Alberta, T3B 6A8
Status
Recruiting
Address
University of Alberta Hospital
Edmonton, Alberta, T6G 2B7
Status
Recruiting
Address
British Columbia Children's Hospital
Vancouver, British Columbia, V6H 3V4
Status
Suspended
Address
CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9
Status
Recruiting
Address
Janeway Child Health Centre
Saint John's, Newfoundland and Labrador, A1B 3V6
Status
Recruiting
Address
IWK Health Centre
Halifax, Nova Scotia, B3K 6R8
Status
Suspended
Address
McMaster Children's Hospital at Hamilton Health Sciences
Hamilton, Ontario, L8N 3Z5
Status
Recruiting
Address
Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7
Status
Suspended
Address
Children's Hospital
London, Ontario, N6A 5W9
Status
Recruiting
Address
Children's Hospital of Eastern Ontario
Ottawa, Ontario, K1H 8L1
Status
Suspended
Address
Hospital for Sick Children
Toronto, Ontario, M5G 1X8
Status
Suspended
Address
The Montreal Children's Hospital of the MUHC
Montreal, Quebec, H3H 1P3
Status
Suspended
Address
Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, H3T 1C5
Status
Active, not recruiting
Address
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Status
Suspended
Address
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4
Status
Suspended
Address
Centre Hospitalier Universitaire de Quebec
Quebec, , G1V 4G2
Status
Suspended
Address
Schneider Children's Medical Center of Israel
Petah Tikua, , 49202
Status
Suspended
Address
Starship Children's Hospital
Grafton, Auckland, 1145
Status
Suspended
Address
Christchurch Hospital
Christchurch, , 8011
Status
Completed
Address
Wellington Children's Hospital
Wellington, , 6002
Status
Suspended
Address
San Jorge Children's Hospital
San Juan, , 00912
Status
Recruiting
Address
University Pediatric Hospital
San Juan, , 00926
Status
Suspended
Address
Swiss Pediatric Oncology Group - Bern
Bern, , 3010
