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Study of Kidney Tumors in Younger Patients
Study Purpose
This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Recruitment Criteria
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Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
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Study Type
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Observational |
| Eligible Ages | N/A - 29 Years |
| Gender | All |
Inclusion Criteria:
- - Patients with the first occurrence of any tumor of the kidney identified on CT scan or MRI are eligible for this study; histologic diagnosis is not required prior to enrollment but is required for all patients once on study.
- - Eligible tumors include (but are not limited to): - Nephroblastic tumors.
- - Nephroblastoma (Wilms' tumor) (favorable histology, anaplasia [diffuse, focal]) - Nephrogenic rests and nephroblastomatosis.
- - Cystic nephroma and cystic partially differentiated nephroblastoma.
- - Metanephric tumors (metanephric adenoma, metanephric adenofibroma, metanephric stromal tumor) - Mesoblastic nephroma (cellular, classic, mixed) - Clear cell sarcoma.
- - Rhabdoid tumor (any malignant rhabdoid tumor occurring outside the central nervous system [CNS]) - Renal epithelioid tumors of childhood (papillary renal cell carcinoma, medullary renal cell carcinoma, renal tumors associated with Xp11.2 translocations, oncocytic renal neoplasms after neuroblastoma) - Angiolipoma.
- - Ossifying renal tumor of infancy.
- - Patients with the first occurrence of the following tumors are also eligible: - Extrarenal nephroblastoma or extrarenal neprogenic rests.
- - Malignant rhabdoid tumor occurring anywhere outside the central nervous system.
- - Required specimens, reports, forms, and copies of imaging studies must be available or will become available for submission and the institution must intend on submitting them as described in the protocol procedures.
- - For ALL patients, (with exception of bilateral, bilaterally predisposed, multicentric, or unilateral tumor in solitary kidney planning to enroll without biopsy***), the following submissions are required: - A complete set of recut hematoxylin and eosin (H & E) slides (including from sampled lymph nodes, if patient had upfront nephrectomy) - * Tissue must be from diagnosis, prior to any renal tumor directed chemotherapy or radiation (only exception is for presumed favorable histology Wilms tumor [FHWT] patients discovered to have diffuse anaplastic Wilms tumor [DAWT] at delayed nephrectomy and plan to enroll at delayed nephrectomy) - Representative formalin-fixed paraffin-embedded tissue block or if a block is unavailable, 10 unstained slides from a representative block of tumor, if available.
- - Tissue must be from diagnosis, prior to any renal tumor directed chemotherapy or radiation (only exception is for presumed FHWT patients discovered to have DAWT at delayed nephrectomy and plan to enroll at delayed nephrectomy) - Institutional pathology report, Specimen Transmittal Form, and Pre-Treatment Pathology Checklist.
- - Copies of images and institutional reports of CT and/or MRI abdomen and pelvis, and Pre Treatment Imaging Checklist.
- - Copies of images and institutional report of chest CT for all malignant tumors.
- - Institutional surgical report(s) and Pre-Treatment Surgical Checklist.
- - CRFs: Staging Checklist and Metastatic Disease Form (if metastatic disease is noted on imaging) - Patients with bilateral, bilaterally predisposed, multicentric, or unilateral tumor in solitary kidney planning to enroll without biopsy via imaging only - these patients will not have central review or have a risk assignment issued, but may contribute to specimen banking for future research.
- - Please note: if the above required items are not received within 120 days of study enrollment, the patient will be considered off study.
- - All patients and/or their parents or legal guardians must sign a written informed consent.
Trial Details
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Trial ID:
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT00898365 |
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Phase
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
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Lead Sponsor
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
Children's Oncology Group |
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Principal Investigator
The person who is responsible for the scientific and technical direction of the entire clinical study. |
Elizabeth A Mullen |
| Principal Investigator Affiliation | Children's Oncology Group |
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Agency Class
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
Other, NIH |
| Overall Status | Active, not recruiting |
| Countries | Australia, Canada, Israel, New Zealand, Puerto Rico, Switzerland, United States |
|
Conditions
The disease, disorder, syndrome, illness, or injury that is being studied. |
Adult Cystic Nephroma, Anaplastic Kidney Wilms Tumor, Angiolipoma, Cellular Congenital Mesoblastic Nephroma, Classic Congenital Mesoblastic Nephroma, Clear Cell Sarcoma of the Kidney, Congenital Mesoblastic Nephroma, Cystic Partially Differentiated Kidney Nephroblastoma, Diffuse Hyperplastic Perilobar Nephroblastomatosis, Extrarenal Rhabdoid Tumor, Kidney Medullary Carcinoma, Kidney Neoplasm, Kidney Oncocytoma, Kidney Wilms Tumor, Metanephric Adenofibroma, Metanephric Adenoma, Metanephric Stromal Tumor, Metanephric Tumor, Mixed Congenital Mesoblastic Nephroma, Ossifying Renal Tumor of Infancy, Papillary Renal Cell Carcinoma, Renal Cell Carcinoma, Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions, Rhabdoid Tumor of the Kidney, Wilms Tumor |
PRIMARY OBJECTIVES:
- I. Classify patients with renal tumors by histological categorization, surgico-pathological stage, presence of metastases, age at diagnosis, tumor weight, and loss of heterozygosity for chromosomes 1p and 16q, to define eligibility for a series of therapeutic studies.
- II. To maintain a biological samples bank to make specimens available to scientists to evaluate additional potential biological prognostic variables and for the conduct of other research by scientists.
- I. To monitor outcome for those patients who are not eligible for a subsequent therapeutic study.
- II. To describe whether the pulmonary tumor burden correlates with outcome in Stage IV patients.
- III. To describe the sensitivity and specificity of abdominal computed tomography (CT) by comparison with surgical and pathologic findings for identification of local tumor spread beyond the renal capsule to adjacent muscle and organs, lymph node involvement at the renal hilum and in the retroperitoneum, preoperative tumor rupture and metastases to the liver.
- IV. To compare the sensitivity and specificity of preoperative abdominal CT and MRI for the identification and differentiation of nephrogenic rests and Wilms tumor in children with multiple renal lesions.
- V. To correlate the method of conception (natural versus assisted reproductive technology) with the development of Wilms tumor.
- VI. To evaluate the frequency of integrase interactor 1 (INI1) mutations in renal and extrarenal malignant rhabdoid tumor of the kidney and to determine the incidence of germline and inherited versus somatic mutations to facilitate clinical correlations on the companion study AREN0321.
Arms
: Ancillary-correlative (renal tumor classification, biology)
Tumor tissue, blood, and urine samples are collected for research studies, including immunohistochemistry. CT scans and MRIs are also performed. Loss of heterozygosity analyses (chromosome 1p and 16q) are performed by extraction of DNA. DNA polymorphisms are assayed by polymerase chain reaction using standard methodology. Leftover specimens are archived for future studies. (LOH and INI1 testing discontinued as of April 2014)
Interventions
Other: - Cytology Specimen Collection Procedure
Correlative studies
Other: - Laboratory Biomarker Analysis
Correlative studies
Contact a Trial Team
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
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Children's Hospital of Alabama
Birmingham, Alabama, 35233
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University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233
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USA Health Strada Patient Care Center
Mobile, Alabama, 36604
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Providence Alaska Medical Center
Anchorage, Alaska, 99508
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Phoenix Childrens Hospital
Phoenix, Arizona, 85016
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Banner University Medical Center - Tucson
Tucson, Arizona, 85719
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202-3591
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University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
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Kaiser Permanente Downey Medical Center
Downey, California, 90242
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010
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Loma Linda University Medical Center
Loma Linda, California, 92354
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Miller Children's and Women's Hospital Long Beach
Long Beach, California, 90806
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Children's Hospital Los Angeles
Los Angeles, California, 90027
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Cedars Sinai Medical Center
Los Angeles, California, 90048
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Mattel Children's Hospital UCLA
Los Angeles, California, 90095
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Valley Children's Hospital
Madera, California, 93636
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Children's Hospital and Research Center at Oakland
Oakland, California, 94609-1809
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Kaiser Permanente-Oakland
Oakland, California, 94611
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Children's Hospital of Orange County
Orange, California, 92868
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Lucile Packard Children's Hospital Stanford University
Palo Alto, California, 94304
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Sutter Medical Center Sacramento
Sacramento, California, 95816
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817
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Rady Children's Hospital - San Diego
San Diego, California, 92123
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Naval Medical Center -San Diego
San Diego, California, 92134
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UCSF Medical Center-Parnassus
San Francisco, California, 94143
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UCSF Medical Center-Mission Bay
San Francisco, California, 94158
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Santa Barbara Cottage Hospital
Santa Barbara, California, 93102
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Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Torrance, California, 90502
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Children's Hospital Colorado
Aurora, Colorado, 80045
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Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center
Denver, Colorado, 80218
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Connecticut Children's Medical Center
Hartford, Connecticut, 06106
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Yale University
New Haven, Connecticut, 06520
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Alfred I duPont Hospital for Children
Wilmington, Delaware, 19803
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MedStar Georgetown University Hospital
Washington, District of Columbia, 20007
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Children's National Medical Center
Washington, District of Columbia, 20010
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Broward Health Medical Center
Fort Lauderdale, Florida, 33316
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Lee Memorial Health System
Fort Myers, Florida, 33901
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Golisano Children's Hospital of Southwest Florida
Fort Myers, Florida, 33908
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University of Florida Health Science Center - Gainesville
Gainesville, Florida, 32610
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Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida, 33021
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Nemours Children's Clinic-Jacksonville
Jacksonville, Florida, 32207
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University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136
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Nicklaus Children's Hospital
Miami, Florida, 33155
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Miami Cancer Institute
Miami, Florida, 33176
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AdventHealth Orlando
Orlando, Florida, 32803
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Arnold Palmer Hospital for Children
Orlando, Florida, 32806
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Nemours Children's Clinic - Orlando
Orlando, Florida, 32806
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UF Cancer Center at Orlando Health
Orlando, Florida, 32806
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Nemours Children's Hospital
Orlando, Florida, 32827
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Nemours Children's Clinic - Pensacola
Pensacola, Florida, 32504
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Johns Hopkins All Children's Hospital
Saint Petersburg, Florida, 33701
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Tampa General Hospital
Tampa, Florida, 33606
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Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa, Florida, 33607
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Saint Mary's Hospital
West Palm Beach, Florida, 33407
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Children's Healthcare of Atlanta - Egleston
Atlanta, Georgia, 30322
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Augusta University Medical Center
Augusta, Georgia, 30912
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Medical Center of Central Georgia
Macon, Georgia, 31201
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Memorial Health University Medical Center
Savannah, Georgia, 31404
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University of Hawaii Cancer Center
Honolulu, Hawaii, 96813
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Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826
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Tripler Army Medical Center
Honolulu, Hawaii, 96859
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Saint Luke's Mountain States Tumor Institute
Boise, Idaho, 83712
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Lurie Children's Hospital-Chicago
Chicago, Illinois, 60611
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University of Illinois
Chicago, Illinois, 60612
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
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Loyola University Medical Center
Maywood, Illinois, 60153
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Advocate Children's Hospital-Oak Lawn
Oak Lawn, Illinois, 60453
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Advocate Children's Hospital-Park Ridge
Park Ridge, Illinois, 60068
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Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068
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Saint Jude Midwest Affiliate
Peoria, Illinois, 61637
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Southern Illinois University School of Medicine
Springfield, Illinois, 62702
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Riley Hospital for Children
Indianapolis, Indiana, 46202
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Saint Vincent Hospital and Health Care Center
Indianapolis, Indiana, 46260
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Blank Children's Hospital
Des Moines, Iowa, 50309
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University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, 52242
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University of Kansas Cancer Center
Kansas City, Kansas, 66160
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University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536
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Norton Children's Hospital
Louisville, Kentucky, 40202
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Tulane University Health Sciences Center
New Orleans, Louisiana, 70112
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Children's Hospital New Orleans
New Orleans, Louisiana, 70118
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Ochsner Medical Center Jefferson
New Orleans, Louisiana, 70121
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Eastern Maine Medical Center
Bangor, Maine, 04401
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Maine Children's Cancer Program
Scarborough, Maine, 04074
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University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201
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Sinai Hospital of Baltimore
Baltimore, Maryland, 21215
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287
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Walter Reed National Military Medical Center
Bethesda, Maryland, 20889-5600
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Floating Hospital for Children at Tufts Medical Center
Boston, Massachusetts, 02111
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215
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Baystate Medical Center
Springfield, Massachusetts, 01199
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UMass Memorial Medical Center - University Campus
Worcester, Massachusetts, 01655
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C S Mott Children's Hospital
Ann Arbor, Michigan, 48109
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Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, 48201
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Ascension Saint John Hospital
Detroit, Michigan, 48236
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Michigan State University Clinical Center
East Lansing, Michigan, 48824-7016
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Hurley Medical Center
Flint, Michigan, 48503
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Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan, 49503
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Bronson Methodist Hospital
Kalamazoo, Michigan, 49007
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Kalamazoo Center for Medical Studies
Kalamazoo, Michigan, 49008
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Beaumont Children's Hospital-Royal Oak
Royal Oak, Michigan, 48073
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William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, 48073
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Children's Hospitals and Clinics of Minnesota - Minneapolis
Minneapolis, Minnesota, 55404
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University of Minnesota/Masonic Cancer Center
Minneapolis, Minnesota, 55455
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905
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University of Mississippi Medical Center
Jackson, Mississippi, 39216
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Columbia Regional
Columbia, Missouri, 65201
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Children's Mercy Hospitals and Clinics
Kansas City, Missouri, 64108
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Cardinal Glennon Children's Medical Center
Saint Louis, Missouri, 63104
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Washington University School of Medicine
Saint Louis, Missouri, 63110
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Mercy Hospital Saint Louis
Saint Louis, Missouri, 63141
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Children's Hospital and Medical Center of Omaha
Omaha, Nebraska, 68114
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University of Nebraska Medical Center
Omaha, Nebraska, 68198
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University Medical Center of Southern Nevada
Las Vegas, Nevada, 89102
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Sunrise Hospital and Medical Center
Las Vegas, Nevada, 89109
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Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada, 89135
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Summerlin Hospital Medical Center
Las Vegas, Nevada, 89144
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Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756
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Hackensack University Medical Center
Hackensack, New Jersey, 07601
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Saint Barnabas Medical Center
Livingston, New Jersey, 07039
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Morristown Medical Center
Morristown, New Jersey, 07960
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Saint Peter's University Hospital
New Brunswick, New Jersey, 08901
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Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital
New Brunswick, New Jersey, 08903
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Newark Beth Israel Medical Center
Newark, New Jersey, 07112
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Saint Joseph's Regional Medical Center
Paterson, New Jersey, 07503
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Overlook Hospital
Summit, New Jersey, 07902
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University of New Mexico Cancer Center
Albuquerque, New Mexico, 87102
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Albany Medical Center
Albany, New York, 12208
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Montefiore Medical Center - Moses Campus
Bronx, New York, 10467
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Brooklyn Hospital Center
Brooklyn, New York, 11201
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Roswell Park Cancer Institute
Buffalo, New York, 14263
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NYU Winthrop Hospital
Mineola, New York, 11501
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The Steven and Alexandra Cohen Children's Medical Center of New York
New Hyde Park, New York, 11040
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016
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Mount Sinai Hospital
New York, New York, 10029
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065
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NYP/Weill Cornell Medical Center
New York, New York, 10065
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University of Rochester
Rochester, New York, 14642
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Stony Brook University Medical Center
Stony Brook, New York, 11794
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State University of New York Upstate Medical University
Syracuse, New York, 13210
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New York Medical College
Valhalla, New York, 10595
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Mission Hospital
Asheville, North Carolina, 28801
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599
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Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina, 28203
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Novant Health Presbyterian Medical Center
Charlotte, North Carolina, 28204
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Duke University Medical Center
Durham, North Carolina, 27710
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East Carolina University
Greenville, North Carolina, 27834
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157
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Sanford Broadway Medical Center
Fargo, North Dakota, 58122
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Children's Hospital Medical Center of Akron
Akron, Ohio, 44308
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229
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Rainbow Babies and Childrens Hospital
Cleveland, Ohio, 44106
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195
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Nationwide Children's Hospital
Columbus, Ohio, 43205
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Dayton Children's Hospital
Dayton, Ohio, 45404
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ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
Toledo, Ohio, 43606
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Mercy Children's Hospital
Toledo, Ohio, 43608
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
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Natalie Warren Bryant Cancer Center at Saint Francis
Tulsa, Oklahoma, 74136
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Legacy Emanuel Children's Hospital
Portland, Oregon, 97227
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Legacy Emanuel Hospital and Health Center
Portland, Oregon, 97227
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Oregon Health and Science University
Portland, Oregon, 97239
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Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, 18103
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Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, 18017
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Geisinger Medical Center
Danville, Pennsylvania, 17822
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Penn State Children's Hospital
Hershey, Pennsylvania, 17033
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
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Saint Christopher's Hospital for Children
Philadelphia, Pennsylvania, 19134
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Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15224
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Rhode Island Hospital
Providence, Rhode Island, 02903
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Medical University of South Carolina
Charleston, South Carolina, 29425
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Prisma Health Richland Hospital
Columbia, South Carolina, 29203
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BI-LO Charities Children's Cancer Center
Greenville, South Carolina, 29605
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Greenville Cancer Treatment Center
Greenville, South Carolina, 29605
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Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134
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T C Thompson Children's Hospital
Chattanooga, Tennessee, 37403
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East Tennessee Childrens Hospital
Knoxville, Tennessee, 37916
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Saint Jude Children's Research Hospital
Memphis, Tennessee, 38105
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The Children's Hospital at TriStar Centennial
Nashville, Tennessee, 37203
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Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, 37232
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Texas Tech University Health Sciences Center-Amarillo
Amarillo, Texas, 79106
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Dell Children's Medical Center of Central Texas
Austin, Texas, 78723
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Driscoll Children's Hospital
Corpus Christi, Texas, 78411
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Medical City Dallas Hospital
Dallas, Texas, 75230
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UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390
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Brooke Army Medical Center
Fort Sam Houston, Texas, 78234
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Cook Children's Medical Center
Fort Worth, Texas, 76104
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Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, 77030
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M D Anderson Cancer Center
Houston, Texas, 77030
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Covenant Children's Hospital
Lubbock, Texas, 79410
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UMC Cancer Center / UMC Health System
Lubbock, Texas, 79415
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Children's Hospital of San Antonio
San Antonio, Texas, 78207
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Methodist Children's Hospital of South Texas
San Antonio, Texas, 78229
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University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229
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Scott and White Memorial Hospital
Temple, Texas, 76508
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Primary Children's Hospital
Salt Lake City, Utah, 84113
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Address
University of Vermont and State Agricultural College
Burlington, Vermont, 05405
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908
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Inova Fairfax Hospital
Falls Church, Virginia, 22042
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Children's Hospital of The King's Daughters
Norfolk, Virginia, 23507
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Naval Medical Center - Portsmouth
Portsmouth, Virginia, 23708-2197
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Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298
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Carilion Children's
Roanoke, Virginia, 24014
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Seattle Children's Hospital
Seattle, Washington, 98105
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Providence Sacred Heart Medical Center and Children's Hospital
Spokane, Washington, 99204
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Mary Bridge Children's Hospital and Health Center
Tacoma, Washington, 98405
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Madigan Army Medical Center
Tacoma, Washington, 98431
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West Virginia University Charleston Division
Charleston, West Virginia, 25304
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Cabell-Huntington Hospital
Huntington, West Virginia, 25701
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Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, 54301
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University of Wisconsin Hospital and Clinics
Madison, Wisconsin, 53792
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Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226
International Sites
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John Hunter Children's Hospital
Hunter Regional Mail Centre, New South Wales, 2310
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Sydney Children's Hospital
Randwick, New South Wales, 2031
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The Children's Hospital at Westmead
Westmead, New South Wales, 2145
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Royal Brisbane and Women's Hospital
Herston, Queensland, 4029
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Royal Children's Hospital-Brisbane
Herston, Queensland, 4029
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Queensland Children's Hospital
South Brisbane, Queensland, 4101
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Women's and Children's Hospital-Adelaide
North Adelaide, South Australia, 5006
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Monash Medical Center-Clayton Campus
Clayton, Victoria, 3168
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Royal Children's Hospital
Parkville, Victoria, 3052
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Princess Margaret Hospital for Children
Perth, Western Australia, 6008
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Perth Children's Hospital
Perth, Western Australia, 6009
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Alberta Children's Hospital
Calgary, Alberta, T3B 6A8
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University of Alberta Hospital
Edmonton, Alberta, T6G 2B7
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British Columbia Children's Hospital
Vancouver, British Columbia, V6H 3V4
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CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9
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Janeway Child Health Centre
Saint John's, Newfoundland and Labrador, A1B 3V6
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IWK Health Centre
Halifax, Nova Scotia, B3K 6R8
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McMaster Children's Hospital at Hamilton Health Sciences
Hamilton, Ontario, L8N 3Z5
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Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7
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Children's Hospital
London, Ontario, N6A 5W9
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Address
Children's Hospital of Eastern Ontario
Ottawa, Ontario, K1H 8L1
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Hospital for Sick Children
Toronto, Ontario, M5G 1X8
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Address
The Montreal Children's Hospital of the MUHC
Montreal, Quebec, H3H 1P3
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Address
Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, H3T 1C5
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Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
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Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4
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Centre Hospitalier Universitaire de Quebec
Quebec, , G1V 4G2
Status
Address
Schneider Children's Medical Center of Israel
Petah Tikua, , 49202
Status
Address
Starship Children's Hospital
Grafton, Auckland, 1145
Status
Address
Christchurch Hospital
Christchurch, , 8011
Status
Address
Wellington Children's Hospital
Wellington, , 6002
Status
Address
San Jorge Children's Hospital
San Juan, , 00912
Status
Address
University Pediatric Hospital
San Juan, , 00926
Status
Address
Swiss Pediatric Oncology Group - Bern
Bern, , 3010
