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Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
Study Purpose
This randomized phase III trial studies how well pembrolizumab works compared with the current standard of care, physician/patient choice of either high-dose recombinant interferon alfa-2B or ipilimumab, in treating patients with stage III-IV melanoma that has been removed by surgery but is likely to come back or spread. High-dose recombinant interferon alfa-2B may help shrink or slow the growth of melanoma. Immunotherapy with monoclonal antibodies, such as ipilimumab and pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. It is not yet known whether pembrolizumab is more effective than the current standard of care in treating patients with melanoma.
Recruitment Criteria
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Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
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Study Type
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Interventional |
| Eligible Ages | 18 Years and Over |
| Gender | All |
Inclusion Criteria:
- - STEP 1 REGISTRATION: - Patients must have completely resected melanoma of cutaneous origin or of unknown primary in order to be eligible for this study; patients must be classified as stage IIIA (N2a), IIIB, IIIC, or stage IV melanoma; patients with non-ulcerated T1b N1a disease are not eligible; patients with melanoma of mucosal or other non-cutaneous origin are eligible; patients with melanoma of ocular origin are not eligible; patients with a history of brain metastases are ineligible.
- - Patients are eligible for this trial either at initial presentation of their melanoma or at the time of the first detected nodal, satellite/in-transit, distant metastases, or recurrent disease in prior lymphadenectomy basin or distant site; nodal, satellite/in-transit metastasis, distant metastases or disease in a prior complete lymphadenectomy basin must have been confirmed histologically by hematoxylin and eosin (H & E) stained slides.
- - Patients with multiple regional nodal basin involvement are eligible; gross or microscopic extracapsular nodal extension is permitted.
- - Patients at initial presentation of melanoma must undergo an adequate wide excision of the primary lesion, if present; patients with previously diagnosed melanoma must have had all current disease resected with pathologically negative margins and must have no evidence of disease at the primary site or must undergo re-resection of the primary site; a full lymphadenectomy meeting the criteria outlined is required for all node-positive patients including those with positive sentinel nodes; patients with recurrent disease who have had a prior complete lymphadenectomy fulfill this requirement as long as all recurrent disease has been resected; for all patients, all disease must have been resected with negative pathological margins and no clinical, radiologic, or pathological evidence of any incompletely resected melanoma; patients must be registered within 98 days of the last surgery performed to render the patient free of disease.
- - Patients must have available and be willing to submit a minimum of five unstained slides from primary, lymph node, or metastatic site to determine PD-L1 expression; the tumor tissue must be adequate for PD-L1 testing (defined as >= 100 tumor cells as confirmed by the treating institution's local pathologist); this must be documented by having a pathologist sign the S1404 Local Pathology Review form prior to step 1 registration; the specimens may come from an archived block but must be submitted within 20 days from cutting the slides.
- - Patients must be offered the opportunity to participate in specimen banking as outlined.
- - Patients must be willing to have blood draws for PK/ADA analysis as outlined, should the patient be randomized to the MK-3475 arm.
- - Patients may have received prior radiation therapy, including after the surgical resection; all adverse events associated with prior surgery and radiation therapy must have resolved to =< grade 1 prior to registration.
- - Patients must not have received neoadjuvant treatment for their melanoma; patients must not have had prior immunotherapy including, but not limited to ipilimumab, interferon alfa-2b, high dose IL-2, pegylated (PEG)-IFN, anti-PD-1, anti-PD-L1 intra-tumoral, or vaccine therapies; patients must not be planning to receive any of the prohibited therapies during the screening or treatment phases of the study.
- - Patients must not be planning to receive concomitant other biologic therapy, radiation therapy, hormonal therapy, other chemotherapy, surgery or other therapy after step 2 registration.
- - All patients must have disease-free status documented by a complete physical examination and imaging studies within 42 days prior to registration; imaging studies must include a total body positron emission tomography (PET)-computed tomography (CT) scan that is of diagnostic quality (with or without brain) or a CT of the chest, abdomen and pelvis; for patients with melanoma arising from the head and neck, dedicated neck imaging (CT with IV contrast or PET-CT through the region) is required; if the patient has had unknown primary with disease in the axilla, neck imaging is required to assure region is clear of cancer; CT imaging should be done with intravenous contrast if there are no contraindications for it; any other clinically-indicated imaging studies if performed (e.g. bone scan) must show no evidence of disease.
- - All patients must have a CT or magnetic resonance imaging (MRI) of the brain within 90 days prior to registration; the brain CT or MRI should be performed with intravenous contrast (unless contraindicated) - Absolute neutrophil count (ANC) >= 1,500 microliter (mcL) (within 42 days prior to registration) - Platelets >= 100,000 mcL (within 42 days prior to registration) - Hemoglobin >= 10 g/dL (within 42 days prior to registration) - Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (except Gilbert's syndrome, who must have a total bilirubin < 3.0 mg/dL) (within 42 days prior to registration) - Serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) and serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) =< 2 x IULN (within 42 days prior to registration) - Alkaline phosphatase =< 2 x IULN (within 42 days prior to registration) - Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min (within 42 days prior to registration) - Patients must have lactate dehydrogenase (LDH) performed within 42 days prior to registration.
- - Patients must have Zubrod performance status =< 1.
- - Patients must have a baseline electrocardiogram (ECG) performed within 42 days of registration that is normal or considered not clinically significant by the site investigator.
- - Patients must not have a history of (non-infectious) pneumonitis that required steroids or current pneumonitis.
- - Patients must not have an active infection requiring systemic therapy.
- - Patients must not have active autoimmune disease that has required systemic treatment in past 2 years (i.e., with use of disease modifying agents, corticosteroids or immunosuppressive drugs); replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment.
- - Patients must not have received live vaccines within 42 days prior to registration; examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, shingles, yellow fever, rabies, bacillus Calmette-Guerin (BCG), and typhoid (oral) vaccine; seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are live attenuated vaccines, and are not allowed.
- - Patients known to be human immunodeficiency virus (HIV) positive are eligible if they meet the following criteria within 30 days prior to registration: stable and adequate cluster of differentiation 4 (CD4) counts (>= 350 mm^3), and serum HIV viral load of < 25,000 IU/ml; patients may be on or off anti-viral therapy so long as they meet the CD4 count criteria.
- - Patients must not have known active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection prior to registration.
- - Patients must not have a history or current evidence of any condition, therapy or laboratory abnormality that might confound the trial results, interfere with the patient's participation for the full duration of the trial, or indicate that participation in the trial is not in the patient's best interests, in the opinion of the treating investigator.
- - No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, lobular carcinoma of the breast in situ, atypical melanocytic hyperplasia or melanoma in situ, adequately treated stage I or II cancer (including multiple primary melanomas) from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for three years.
- - Women of childbearing potential must have a negative urine or serum pregnancy test within 28 days prior to registration; women/men of reproductive potential must have agreed to use an effective contraceptive method for the course of the study through 120 days after the last dose of study medication; should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy, or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures, he/she is responsible for beginning contraceptive measures; patients must not be pregnant or nursing due to unknown teratogenic side effects.
- - Patients who are able to complete questionnaires in English, Spanish or French must participate in the quality of life assessments; (those patients who cannot complete the quality of life questionnaires in English, Spanish or French can be registered to S1404 without contributing to the quality of life studies) - Patients must be informed of the investigational nature of this study and must sign and give written informed consent for this protocol in accordance with institutional and federal guidelines.
- - As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system.
- - STEP 2 REGISTRATION (RANDOMIZATION CRITERIA): - Patients must not be registered until receiving confirmation from the Southwest Oncology Group (SWOG) Statistical Center that the patient's tissue specimen was adequate for PD-L1 testing; patients must be registered within 7 working days of receiving the e-mail notification.
- - Women of childbearing potential must plan to have a urine or serum pregnancy test within 72 hours prior to receiving the first dose of study medication; if the urine test is positive or cannot be confirmed as negative, a negative serum pregnancy test will be required.
Trial Details
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Trial ID:
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT02506153 |
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Phase
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
Phase 3 |
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Lead Sponsor
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
National Cancer Institute (NCI) |
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Principal Investigator
The person who is responsible for the scientific and technical direction of the entire clinical study. |
Sapna Patel |
| Principal Investigator Affiliation | SWOG Cancer Research Network |
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Agency Class
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
NIH |
| Overall Status | Active, not recruiting |
| Countries | Canada, Ireland, United States |
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Conditions
The disease, disorder, syndrome, illness, or injury that is being studied. |
Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Cutaneous Melanoma, Metastatic Mucosal Melanoma, Metastatic Non-Cutaneous Melanoma, Non-Cutaneous Melanoma, Recurrent Cutaneous Melanoma, Recurrent Mucosal Melanoma, Recurrent Non-Cutaneous Melanoma |
PRIMARY OBJECTIVES:
- I. To compare overall survival (OS) of patients with resected stage III and IV melanoma treated with physician/patient choice of either high dose interferon recombinant interferon alfa-2b (alfa-2b) or ipilimumab versus MK-3475 (pembrolizumab).
- II. Among patients who are PD-L1 positive, to compare OS of patients with resected stage III and IV melanoma treated with physician/patient choice of either high dose interferon alfa-2b or ipilimumab versus MK-3475 (pembrolizumab).
- III. To compare relapse-free survival (RFS) of patients with resected stage III and IV melanoma treated with physician/patient choice of either high dose interferon alfa-2b or ipilimumab to MK-3475 (pembrolizumab).
- I. To estimate OS and RFS for patients who are PD-L1 negative or PD-L1 indeterminate in this population.
- II. To compare OS and RFS of patients between the two arms within PD-L1 positive and negative subgroups and to look at the interaction between PD-L1 (positive versus negative) and treatment arm.
- III. To assess the safety and tolerability of the regimens.
- I. To bank tissue and whole blood in anticipation of future correlative studies in this patient population.
- II. To evaluate PD-L1 expression through immunohistochemistry assay.
- III. To evaluate the effect of treatment-related side effects that may have an impact on the health-related domains of quality of life (QOL) using the Functional Assessment of Cancer Therapy (FACT)-Biological Response Modifiers (BRM), European Quality of Life Five Dimension Three Level Scale (EQ-5D-3L), and Functional Assessment of Chronic Illness Therapy Diarrhea (FACIT-D) between patients treated with physician/patient choice of either high-dose interferon alfa-2b or ipilimumab and MK-3475 (pembrolizumab).
- IV. Pharmacokinetic (PK) and anti-drug antibody (ADA) testing will be performed on all patients receiving MK-3475 (pembrolizumab).
- I. To evaluate the association between TCR beta variable gene (TRBV) haplotype and grade 3-4 immune-related adverse events (irAEs) among stage III melanoma patients treated with adjuvant ipilimumab or pembrolizumab.
- II. To describe the TRBV haplotype distribution among this cohort of patients studied.
- I. To evaluate associations between pretreatment ctDNA (present versus absent) and relapse within 2 years of randomization in a case-control analysis across treatment arms.
- II. To evaluate associations between pretreatment ctDNA (present versus absent) and relapse within 2 years of randomization in a case-control analysis across treatment arms.
- III. To evaluate associations between pretreatment ctDNA and relapse within 2 years of randomization in a case-control analysis within each treatment arm (after treatment arm data are unblinded to investigators).
- IV. To evaluate associations between "early-on treatment" ctDNA levels and relapse within 2 years of randomization.
- V. To describe ctDNA levels at end of therapy and time of relapse.
Arms
Active Comparator: Arm I (high-dose recombinant interferon alfa-2B, ipilimumab)
INDUCTION THERAPY: Patients receive high-dose recombinant interferon alfa-2B intravenously (IV) over 20 minutes on days 1-5. Treatment repeats weekly for 4 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 3 weeks for a total of 4 cycles in the absence of disease progression or unacceptable toxicity. MAINTENANCE THERAPY: Patients receive high-dose recombinant interferon alfa-2B subcutaneously (SC) on days 1, 3, and 5. Treatment repeats every 6 weeks for up to 48 weeks in the absence of disease progression or unacceptable toxicity. Or patients receive ipilimumab IV over 90 minutes on day 1. Treatment repeats every 12 weeks for 3 years in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Experimental: Arm II (pembrolizumab)
Patients receive pembrolizumab IV over 30 minutes on day 1. Treatment repeats every 3 weeks for up to 52 weeks in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan, PET scan, MRI and blood sample collection throughout the study.
Interventions
Procedure: - Biospecimen Collection
Undergo blood sample collection
Procedure: - Computed Tomography
Undergo CT scan
Biological: - Ipilimumab
Given IV
Procedure: - Magnetic Resonance Imaging
Undergo MRI
Biological: - Pembrolizumab
Given IV
Procedure: - Positron Emission Tomography
Undergo PET scan
Other: - Quality-of-Life Assessment
Ancillary studies
Biological: - Recombinant Interferon Alfa-2b
Given IV and SC
Contact a Trial Team
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
Status
Address
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233
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Cancer Center at Saint Joseph's
Phoenix, Arizona, 85004
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Virginia G Piper Cancer Care-Del Camino
Scottsdale, Arizona, 85258
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Banner University Medical Center - Tucson
Tucson, Arizona, 85719
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University of Arizona Cancer Center-North Campus
Tucson, Arizona, 85719
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Address
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
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Address
Highlands Oncology Group - Rogers
Rogers, Arkansas, 72758
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Kaiser Permanente-Anaheim
Anaheim, California, 92806
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Sutter Auburn Faith Hospital
Auburn, California, 95602
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Kaiser Permanente-Baldwin Park
Baldwin Park, California, 91706
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Kaiser Permanente-Bellflower
Bellflower, California, 90706
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UC Irvine Health Cancer Center-Newport
Costa Mesa, California, 92627
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Address
City of Hope Comprehensive Cancer Center
Duarte, California, 91010
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Address
Kaiser Permanente-Fontana
Fontana, California, 92335
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Kaiser Permanente-Fremont
Fremont, California, 94538
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Palo Alto Medical Foundation-Fremont
Fremont, California, 94538
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Kaiser Permanente-Fresno
Fresno, California, 93720
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Kaiser Permanente South Bay
Harbor City, California, 90710
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Kaiser Permanente-Irvine
Irvine, California, 92618
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UC San Diego Moores Cancer Center
La Jolla, California, 92093
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Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, 90027
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Los Angeles General Medical Center
Los Angeles, California, 90033
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Address
USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033
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Address
Kaiser Permanente West Los Angeles
Los Angeles, California, 90034
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Address
Cedars Sinai Medical Center
Los Angeles, California, 90048
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Address
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095
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Address
Fremont - Rideout Cancer Center
Marysville, California, 95901
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Address
Memorial Medical Center
Modesto, California, 95355
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Address
Kaiser Permanente-Modesto
Modesto, California, 95356
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Address
Palo Alto Medical Foundation-Camino Division
Mountain View, California, 94040
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Address
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663
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Address
Sutter Cancer Research Consortium
Novato, California, 94945
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Address
Kaiser Permanente-Oakland
Oakland, California, 94611
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Saint Joseph Hospital - Orange
Orange, California, 92868
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868
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Address
Palo Alto Medical Foundation Health Care
Palo Alto, California, 94301
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Stanford Cancer Institute Palo Alto
Palo Alto, California, 94304
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Kaiser Permanente - Panorama City
Panorama City, California, 91402
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Kaiser Permanente-Redwood City
Redwood City, California, 94063
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Kaiser Permanente-Richmond
Richmond, California, 94801
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Kaiser Permanente-Riverside
Riverside, California, 92505
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Kaiser Permanente-Roseville
Roseville, California, 95661
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Sutter Roseville Medical Center
Roseville, California, 95661
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Address
Sutter Medical Center Sacramento
Sacramento, California, 95816
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817
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Address
Kaiser Permanente-South Sacramento
Sacramento, California, 95823
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Kaiser Permanente Sacramento Medical Center
Sacramento, California, 95825
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Address
Kaiser Permanente-San Diego Mission
San Diego, California, 92108
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Address
Kaiser Permanente-San Diego Zion
San Diego, California, 92120
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California Pacific Medical Center-Pacific Campus
San Francisco, California, 94115
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Address
Kaiser Permanente-San Francisco
San Francisco, California, 94115
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Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, 95119
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Kaiser Permanente San Leandro
San Leandro, California, 94577
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Kaiser Permanente-San Marcos
San Marcos, California, 92078
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Address
Kaiser Permanente-San Rafael
San Rafael, California, 94903
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Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, 95051
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Address
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California, 95065
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Address
Kaiser Permanente-Santa Rosa
Santa Rosa, California, 95403
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Address
Sutter Pacific Medical Foundation
Santa Rosa, California, 95403
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Address
Kaiser Permanente-South San Francisco
South San Francisco, California, 94080
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Address
Kaiser Permanente-Stockton
Stockton, California, 95210
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Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California, 94086
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Address
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California, 96161
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Address
Kaiser Permanente Medical Center-Vacaville
Vacaville, California, 95688
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Kaiser Permanente-Vallejo
Vallejo, California, 94589
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Kaiser Permanente-Walnut Creek
Walnut Creek, California, 94596
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Address
Kaiser Permanente-Woodland Hills
Woodland Hills, California, 91367
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Address
UCHealth University of Colorado Hospital
Aurora, Colorado, 80045
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Address
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, 80907
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Address
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, 80909
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Address
Kaiser Permanente-Franklin
Denver, Colorado, 80205
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Address
AdventHealth Porter
Denver, Colorado, 80210
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Address
Saint Joseph Hospital - Cancer Centers of Colorado
Denver, Colorado, 80218
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Address
Poudre Valley Hospital
Fort Collins, Colorado, 80524
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Address
Banner North Colorado Medical Center
Greeley, Colorado, 80631
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Address
Kaiser Permanente-Rock Creek
Lafayette, Colorado, 80026
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Address
AdventHealth Littleton
Littleton, Colorado, 80122
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Kaiser Permanente-Lone Tree
Lone Tree, Colorado, 80124
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AdventHealth Parker
Parker, Colorado, 80138
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Address
Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut, 06824
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Address
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, 06105
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Address
Yale University
New Haven, Connecticut, 06520
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Address
Stamford Hospital/Bennett Cancer Center
Stamford, Connecticut, 06904
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Address
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, 06611
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Address
Helen F Graham Cancer Center
Newark, Delaware, 19713
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Address
Medical Oncology Hematology Consultants PA
Newark, Delaware, 19713
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Address
Christiana Care Health System-Christiana Hospital
Newark, Delaware, 19718
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Address
Beebe Health Campus
Rehoboth Beach, Delaware, 19971
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Address
MedStar Georgetown University Hospital
Washington, District of Columbia, 20007
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Address
MedStar Washington Hospital Center
Washington, District of Columbia, 20010
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Address
Lakeland Regional Health Hollis Cancer Center
Lakeland, Florida, 33805
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Address
Mount Sinai Medical Center
Miami Beach, Florida, 33140
Status
Address
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136
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Address
Orlando Health Cancer Institute
Orlando, Florida, 32806
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Address
Moffitt Cancer Center
Tampa, Florida, 33612
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Address
Cleveland Clinic-Weston
Weston, Florida, 33331
Status
Address
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322
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Address
Northside Hospital
Atlanta, Georgia, 30342
Status
Address
Northside Hospital-Forsyth
Cumming, Georgia, 30041
Status
Address
Memorial Health University Medical Center
Savannah, Georgia, 31404
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Address
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia, 31405
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Address
South Georgia Medical Center/Pearlman Cancer Center
Valdosta, Georgia, 31602
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Address
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, 96813
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Address
Island Urology
Honolulu, Hawaii, 96813
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Address
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, 96813
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Address
Queen's Medical Center
Honolulu, Hawaii, 96813
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Address
Straub Clinic and Hospital
Honolulu, Hawaii, 96813
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Address
University of Hawaii Cancer Center
Honolulu, Hawaii, 96813
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Address
Hawaii Cancer Care Inc-Liliha
Honolulu, Hawaii, 96817
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Address
Queen's Cancer Center - Kuakini
Honolulu, Hawaii, 96817
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Address
Tripler Army Medical Center
Honolulu, Hawaii, 96859
Status
Address
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, 83706
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Address
Saint Luke's Cancer Institute - Boise
Boise, Idaho, 83712
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Address
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, 83814
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Address
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, 83619
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Address
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, 83642
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Address
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, 83687
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Address
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, 83854
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Address
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho, 83864
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Address
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, 83301
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Address
Rush - Copley Medical Center
Aurora, Illinois, 60504
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Address
Illinois CancerCare-Bloomington
Bloomington, Illinois, 61704
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Address
Illinois CancerCare-Canton
Canton, Illinois, 61520
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Address
Centralia Oncology Clinic
Centralia, Illinois, 62801
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Address
Northwestern University
Chicago, Illinois, 60611
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Address
Rush University Medical Center
Chicago, Illinois, 60612
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Address
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
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Address
Carle at The Riverfront
Danville, Illinois, 61832
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Address
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, 62526
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Address
Decatur Memorial Hospital
Decatur, Illinois, 62526
Status
Address
Carle Physician Group-Effingham
Effingham, Illinois, 62401
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Address
Crossroads Cancer Center
Effingham, Illinois, 62401
Status
Address
Elmhurst Memorial Hospital
Elmhurst, Illinois, 60126
Status
Address
Illinois CancerCare-Eureka
Eureka, Illinois, 61530
Status
Address
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, 60201
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Address
Illinois CancerCare-Galesburg
Galesburg, Illinois, 61401
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Address
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, 60134
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Address
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, 60026
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Address
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, 60035
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Address
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, 61443
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Address
Illinois CancerCare-Macomb
Macomb, Illinois, 61455
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Address
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, 61938
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Address
Loyola University Medical Center
Maywood, Illinois, 60153
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Address
Edward Hospital/Cancer Center
Naperville, Illinois, 60540
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Address
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, 60451
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Address
Cancer Care Center of O'Fallon
O'Fallon, Illinois, 62269
Status
Address
University of Chicago Medicine-Orland Park
Orland Park, Illinois, 60462
Status
Address
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350
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Address
Illinois CancerCare-Pekin
Pekin, Illinois, 61554
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Address
Illinois CancerCare-Peoria
Peoria, Illinois, 61615
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Address
Illinois CancerCare-Peru
Peru, Illinois, 61354
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Address
Edward Hospital/Cancer Center?Plainfield
Plainfield, Illinois, 60585
Status
Address
Illinois CancerCare-Princeton
Princeton, Illinois, 61356
Status
Address
UW Health Carbone Cancer Center Rockford
Rockford, Illinois, 61114
Status
Address
Central Illinois Hematology Oncology Center
Springfield, Illinois, 62702
Status
Address
Southern Illinois University School of Medicine
Springfield, Illinois, 62702
Status
Address
Springfield Clinic
Springfield, Illinois, 62702
Status
Address
Springfield Memorial Hospital
Springfield, Illinois, 62781
Status
Address
Carle Cancer Center
Urbana, Illinois, 61801
Status
Address
The Carle Foundation Hospital
Urbana, Illinois, 61801
Status
Address
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, 60555
Status
Address
Rush-Copley Healthcare Center
Yorkville, Illinois, 60560
Status
Address
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202
Status
Address
Community Cancer Center East
Indianapolis, Indiana, 46219
Status
Address
Community Cancer Center South
Indianapolis, Indiana, 46227
Status
Address
Franciscan Health Indianapolis
Indianapolis, Indiana, 46237
Status
Address
Community Cancer Center North
Indianapolis, Indiana, 46256
Status
Address
Franciscan Health Mooresville
Mooresville, Indiana, 46158
Status
Address
Reid Health
Richmond, Indiana, 47374
Status
Address
Mary Greeley Medical Center
Ames, Iowa, 50010
Status
Address
McFarland Clinic - Ames
Ames, Iowa, 50010
Status
Address
McFarland Clinic - Boone
Boone, Iowa, 50036
Status
Address
Physicians' Clinic of Iowa PC
Cedar Rapids, Iowa, 52402
Status
Address
Mercy Cancer Center-West Lakes
Clive, Iowa, 50325
Status
Address
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa, 50325
Status
Address
Iowa Methodist Medical Center
Des Moines, Iowa, 50309
Status
Address
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, 50309
Status
Address
Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314
Status
Address
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa, 50314
Status
Address
McFarland Clinic - Trinity Cancer Center
Fort Dodge, Iowa, 50501
Status
Address
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, 52242
Status
Address
McFarland Clinic - Jefferson
Jefferson, Iowa, 50129
Status
Address
McFarland Clinic - Marshalltown
Marshalltown, Iowa, 50158
Status
Address
Mercy Medical Center-West Lakes
West Des Moines, Iowa, 50266
Status
Address
Cancer Center of Kansas - Chanute
Chanute, Kansas, 66720
Status
Address
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, 67801
Status
Address
Cancer Center of Kansas - El Dorado
El Dorado, Kansas, 67042
Status
Address
Saint Catherine Hospital
Garden City, Kansas, 67846
Status
Address
Central Care Cancer Center - Great Bend
Great Bend, Kansas, 67530
Status
Address
Saint Rose Ambulatory and Surgery Center
Great Bend, Kansas, 67530
Status
Address
HaysMed
Hays, Kansas, 67601
Status
Address
University of Kansas Cancer Center-West
Kansas City, Kansas, 66112
Status
Address
University of Kansas Cancer Center
Kansas City, Kansas, 66160
Status
Address
Lawrence Memorial Hospital
Lawrence, Kansas, 66044
Status
Address
Kansas Institute of Medicine Cancer and Blood Center
Lenexa, Kansas, 66219
Status
Address
Minimally Invasive Surgery Hospital
Lenexa, Kansas, 66219
Status
Address
Cancer Center of Kansas-Liberal
Liberal, Kansas, 67905
Status
Address
Cancer Center of Kansas - McPherson
McPherson, Kansas, 67460
Status
Address
Cancer Center of Kansas - Newton
Newton, Kansas, 67114
Status
Address
The University of Kansas Cancer Center - Olathe
Olathe, Kansas, 66061
Status
Address
Menorah Medical Center
Overland Park, Kansas, 66209
Status
Address
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, 66210
Status
Address
Saint Luke's South Hospital
Overland Park, Kansas, 66213
Status
Address
Cancer Center of Kansas - Parsons
Parsons, Kansas, 67357
Status
Address
Mercy Hospital Pittsburg
Pittsburg, Kansas, 66762
Status
Address
Cancer Center of Kansas - Salina
Salina, Kansas, 67401
Status
Address
Salina Regional Health Center
Salina, Kansas, 67401
Status
Address
University of Kansas Health System Saint Francis Campus
Topeka, Kansas, 66606
Status
Address
Cancer Center of Kansas - Wellington
Wellington, Kansas, 67152
Status
Address
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas, 67208
Status
Address
Ascension Via Christi Hospitals Wichita
Wichita, Kansas, 67214
Status
Address
Cancer Center of Kansas - Wichita
Wichita, Kansas, 67214
Status
Address
Cancer Center of Kansas - Winfield
Winfield, Kansas, 67156
Status
Address
Flaget Memorial Hospital
Bardstown, Kentucky, 40004
Status
Address
Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky, 40504
Status
Address
Saint Joseph Hospital East
Lexington, Kentucky, 40509
Status
Address
Saints Mary and Elizabeth Hospital
Louisville, Kentucky, 40215
Status
Address
UofL Health Medical Center Northeast
Louisville, Kentucky, 40245
Status
Address
Owensboro Health Mitchell Memorial Cancer Center
Owensboro, Kentucky, 42303
Status
Address
LSU Health Baton Rouge-North Clinic
Baton Rouge, Louisiana, 70805
Status
Address
Our Lady of the Lake Physician Group
Baton Rouge, Louisiana, 70808
Status
Address
Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana, 70809
Status
Address
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, 70809
Status
Address
Northshore Oncology Associates-Covington
Covington, Louisiana, 70433
Status
Address
Ochsner LSU Health Monroe Medical Center
Monroe, Louisiana, 71202
Status
Address
LSU Health Sciences Center at Shreveport
Shreveport, Louisiana, 71103
Status
Address
Harold Alfond Center for Cancer Care
Augusta, Maine, 04330
Status
Address
Eastern Maine Medical Center
Bangor, Maine, 04401
Status
Address
Lafayette Family Cancer Center-EMMC
Brewer, Maine, 04412
Status
Address
New England Cancer Specialists
Westbrook, Maine, 04092
Status
Address
Mercy Medical Center
Baltimore, Maryland, 21202
Status
Address
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland, 21237
Status
Address
Frederick Memorial Hospital
Frederick, Maryland, 21701
Status
Address
Beverly Hospital
Beverly, Massachusetts, 01915
Status
Address
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114
Status
Address
Boston Medical Center
Boston, Massachusetts, 02118
Status
Address
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215
Status
Address
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215
Status
Address
Lahey Hospital and Medical Center
Burlington, Massachusetts, 01805
Status
Address
Addison Gilbert Hospital
Gloucester, Massachusetts, 01930
Status
Address
Baystate Medical Center
Springfield, Massachusetts, 01199
Status
Address
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109
Status
Address
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, 48201
Status
Address
Henry Ford Hospital
Detroit, Michigan, 48202
Status
Address
Henry Ford Health Saint John Hospital
Detroit, Michigan, 48236
Status
Address
Henry Ford River District Hospital
East China Township, Michigan, 48054
Status
Address
OSF Saint Francis Hospital and Medical Group
Escanaba, Michigan, 49829
Status
Address
Genesys Hurley Cancer Institute
Flint, Michigan, 48503
Status
Address
Hurley Medical Center
Flint, Michigan, 48503
Status
Address
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan, 49503
Status
Address
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan, 49503
Status
Address
Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods, Michigan, 48236
Status
Address
Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods, Michigan, 48236
Status
Address
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods, Michigan, 48236
Status
Address
Allegiance Health
Jackson, Michigan, 49201
Status
Address
West Michigan Cancer Center
Kalamazoo, Michigan, 49007
Status
Address
University of Michigan Health - Sparrow Lansing
Lansing, Michigan, 48912
Status
Address
Henry Ford Saint John Hospital - Macomb Medical
Macomb, Michigan, 48044
Status
Address
Henry Ford Warren Hospital - Breast Macomb
Macomb, Michigan, 48044
Status
Address
Trinity Health Muskegon Hospital
Muskegon, Michigan, 49444
Status
Address
Corewell Health Reed City Hospital
Reed City, Michigan, 49677
Status
Address
Henry Ford Rochester Hospital
Rochester Hills, Michigan, 48309
Status
Address
MyMichigan Medical Center Saginaw
Saginaw, Michigan, 48601
Status
Address
Munson Medical Center
Traverse City, Michigan, 49684
Status
Address
Henry Ford Health Warren Hospital
Warren, Michigan, 48093
Status
Address
Henry Ford Warren Hospital - GLCMS
Warren, Michigan, 48093
Status
Address
University of Michigan Health - West
Wyoming, Michigan, 49519
Status
Address
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota, 56601
Status
Address
Fairview Ridges Hospital
Burnsville, Minnesota, 55337
Status
Address
Mercy Hospital
Coon Rapids, Minnesota, 55433
Status
Address
Essentia Health Cancer Center
Duluth, Minnesota, 55805
Status
Address
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, 55805
Status
Address
Miller-Dwan Hospital
Duluth, Minnesota, 55805
Status
Address
Fairview Southdale Hospital
Edina, Minnesota, 55435
Status
Address
Lake Region Healthcare Corporation-Cancer Care
Fergus Falls, Minnesota, 56537
Status
Address
Unity Hospital
Fridley, Minnesota, 55432
Status
Address
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, 55109
Status
Address
Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109
Status
Address
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407
Status
Address
Hennepin County Medical Center
Minneapolis, Minnesota, 55415
Status
Address
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416
Status
Address
Regions Hospital
Saint Paul, Minnesota, 55101
Status
Address
United Hospital
Saint Paul, Minnesota, 55102
Status
Address
Ridgeview Medical Center
Waconia, Minnesota, 55387
Status
Address
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, 55125
Status
Address
University of Mississippi Medical Center
Jackson, Mississippi, 39216
Status
Address
Parkland Health Center-Bonne Terre
Bonne Terre, Missouri, 63628
Status
Address
Mercy Cancer Center - Cape Girardeau
Cape Girardeau, Missouri, 63703
Status
Address
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703
Status
Address
Centerpoint Medical Center LLC
Independence, Missouri, 64057
Status
Address
MU Health Care Goldschmidt Cancer Center
Jefferson City, Missouri, 65109
Status
Address
University Health Truman Medical Center
Kansas City, Missouri, 64108
Status
Address
Saint Luke's Hospital of Kansas City
Kansas City, Missouri, 64111
Status
Address
Heartland Hematology and Oncology Associates Incorporated
Kansas City, Missouri, 64118
Status
Address
Kansas City Veterans Affairs Medical Center
Kansas City, Missouri, 64128
Status
Address
The University of Kansas Cancer Center-South
Kansas City, Missouri, 64131
Status
Address
Research Medical Center
Kansas City, Missouri, 64132
Status
Address
University of Kansas Cancer Center - North
Kansas City, Missouri, 64154
Status
Address
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri, 64064
Status
Address
Saint Luke's East - Lee's Summit
Lee's Summit, Missouri, 64086
Status
Address
Liberty Radiation Oncology Center
Liberty, Missouri, 64068
Status
Address
Heartland Regional Medical Center
Saint Joseph, Missouri, 64506
Status
Address
Missouri Baptist Medical Center
Saint Louis, Missouri, 63131
Status
Address
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, 63670
Status
Address
Mercy Hospital Springfield
Springfield, Missouri, 65804
Status
Address
CoxHealth South Hospital
Springfield, Missouri, 65807
Status
Address
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, 63080
Status
Address
Community Hospital of Anaconda
Anaconda, Montana, 59711
Status
Address
Billings Clinic Cancer Center
Billings, Montana, 59101
Status
Address
Saint Vincent Healthcare
Billings, Montana, 59101
Status
Address
Bozeman Health Deaconess Hospital
Bozeman, Montana, 59715
Status
Address
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, 59701
Status
Address
Benefis Sletten Cancer Institute
Great Falls, Montana, 59405
Status
Address
Great Falls Clinic
Great Falls, Montana, 59405
Status
Address
Saint Peter's Community Hospital
Helena, Montana, 59601
Status
Address
Logan Health Medical Center
Kalispell, Montana, 59901
Status
Address
Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802
Status
Address
Community Medical Center
Missoula, Montana, 59804
Status
Address
Nebraska Cancer Specialists/Oncology Hematology West PC
Grand Island, Nebraska, 68803
Status
Address
Nebraska Hematology and Oncology
Lincoln, Nebraska, 68506
Status
Address
Cancer Partners of Nebraska
Lincoln, Nebraska, 68516
Status
Address
Faith Regional Health Services Carson Cancer Center
Norfolk, Nebraska, 68701
Status
Address
Nebraska Methodist Hospital
Omaha, Nebraska, 68114
Status
Address
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122
Status
Address
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124
Status
Address
Nebraska Cancer Specialists - Omaha
Omaha, Nebraska, 68124
Status
Address
Alegent Health Lakeside Hospital
Omaha, Nebraska, 68130
Status
Address
Creighton University Medical Center
Omaha, Nebraska, 68131
Status
Address
Regional West Medical Center Cancer Center
Scottsbluff, Nebraska, 69361
Status
Address
Cancer and Blood Specialists-Henderson
Henderson, Nevada, 89052
Status
Address
Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada, 89052
Status
Address
Las Vegas Cancer Center-Henderson
Henderson, Nevada, 89052
Status
Address
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson, Nevada, 89074
Status
Address
GenesisCare USA - Henderson
Henderson, Nevada, 89074
Status
Address
University Medical Center of Southern Nevada
Las Vegas, Nevada, 89102
Status
Address
GenesisCare USA - Las Vegas
Las Vegas, Nevada, 89109
Status
Address
Cancer Therapy and Integrative Medicine
Las Vegas, Nevada, 89121
Status
Address
Ann M Wierman MD LTD
Las Vegas, Nevada, 89128
Status
Address
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada, 89128
Status
Address
Las Vegas Cancer Center-Medical Center
Las Vegas, Nevada, 89148-2405
Status
Address
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, 89148
Status
Address
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada, 89148
Status
Address
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada, 89169
Status
Address
University Cancer Center
Las Vegas, Nevada, 89169
Status
Address
Wentworth-Douglass Hospital
Dover, New Hampshire, 03820
Status
Address
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, 03756
Status
Address
Dartmouth Cancer Center - Manchester
Manchester, New Hampshire, 03102
Status
Address
Saint Joseph Hospital
Nashua, New Hampshire, 03060
Status
Address
Dartmouth Cancer Center - Nashua
Nashua, New Hampshire, 03063
Status
Address
Veterans Adminstration New Jersey Health Care System
East Orange, New Jersey, 07018-1095
Status
Address
Hackensack University Medical Center
Hackensack, New Jersey, 07601
Status
Address
Saint Barnabas Medical Center
Livingston, New Jersey, 07039
Status
Address
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903
Status
Address
Lovelace Medical Center-Saint Joseph Square
Albuquerque, New Mexico, 87102
Status
Address
Southwest Gynecologic Oncology Associates Inc
Albuquerque, New Mexico, 87106
Status
Address
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106
Status
Address
Hematology Oncology Associates of Central New York-Auburn
Auburn, New York, 13021
Status
Address
Roswell Park Cancer Institute
Buffalo, New York, 14263
Status
Address
Hematology Oncology Associates of CNY at Camillus
Camillus, New York, 13031
Status
Address
Hematology Oncology Associates of Central New York-East Syracuse
East Syracuse, New York, 13057
Status
Address
Glens Falls Hospital
Glens Falls, New York, 12801
Status
Address
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032
Status
Address
Rochester General Hospital
Rochester, New York, 14621
Status
Address
University of Rochester
Rochester, New York, 14642
Status
Address
Stony Brook University Medical Center
Stony Brook, New York, 11794
Status
Address
State University of New York Upstate Medical University
Syracuse, New York, 13210
Status
Address
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599
Status
Address
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina, 28328
Status
Address
Duke University Medical Center
Durham, North Carolina, 27710
Status
Address
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina, 27534
Status
Address
Wayne Memorial Hospital
Goldsboro, North Carolina, 27534
Status
Address
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina, 28791
Status
Address
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina, 28546
Status
Address
Sanford Bismarck Medical Center
Bismarck, North Dakota, 58501
Status
Address
Sanford Broadway Medical Center
Fargo, North Dakota, 58122
Status
Address
Sanford Roger Maris Cancer Center
Fargo, North Dakota, 58122
Status
Address
Altru Cancer Center
Grand Forks, North Dakota, 58201
Status
Address
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio, 44122
Status
Address
Strecker Cancer Center-Belpre
Belpre, Ohio, 45714
Status
Address
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, 45459
Status
Address
Miami Valley Hospital South
Centerville, Ohio, 45459
Status
Address
Adena Regional Medical Center
Chillicothe, Ohio, 45601
Status
Address
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, 45219
Status
Address
Case Western Reserve University
Cleveland, Ohio, 44106
Status
Address
MetroHealth Medical Center
Cleveland, Ohio, 44109
Status
Address
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio, 44111
Status
Address
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
Status
Address
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210
Status
Address
Mount Carmel East Hospital
Columbus, Ohio, 43213
Status
Address
Columbus Oncology and Hematology Associates Inc
Columbus, Ohio, 43214
Status
Address
Riverside Methodist Hospital
Columbus, Ohio, 43214
Status
Address
Grant Medical Center
Columbus, Ohio, 43215
Status
Address
The Mark H Zangmeister Center
Columbus, Ohio, 43219
Status
Address
Mount Carmel Health Center West
Columbus, Ohio, 43222
Status
Address
Doctors Hospital
Columbus, Ohio, 43228
Status
Address
Good Samaritan Hospital - Dayton
Dayton, Ohio, 45406
Status
Address
Miami Valley Hospital
Dayton, Ohio, 45409
Status
Address
Dayton Physician LLC - Englewood
Dayton, Ohio, 45415
Status
Address
Miami Valley Hospital North
Dayton, Ohio, 45415
Status
Address
Delaware Health Center-Grady Cancer Center
Delaware, Ohio, 43015
Status
Address
Grady Memorial Hospital
Delaware, Ohio, 43015
Status
Address
Armes Family Cancer Center
Findlay, Ohio, 45840
Status
Address
Blanchard Valley Hospital
Findlay, Ohio, 45840
Status
Address
Orion Cancer Care
Findlay, Ohio, 45840
Status
Address
Cleveland Clinic Cancer Center Independence
Independence, Ohio, 44131
Status
Address
Greater Dayton Cancer Center
Kettering, Ohio, 45409
Status
Address
Kettering Medical Center
Kettering, Ohio, 45429
Status
Address
OhioHealth Mansfield Hospital
Mansfield, Ohio, 44903
Status
Address
Cleveland Clinic Cancer Center Mansfield
Mansfield, Ohio, 44906
Status
Address
Marietta Memorial Hospital
Marietta, Ohio, 45750
Status
Address
OhioHealth Marion General Hospital
Marion, Ohio, 43302
Status
Address
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, 44124
Status
Address
Knox Community Hospital
Mount Vernon, Ohio, 43050
Status
Address
Licking Memorial Hospital
Newark, Ohio, 43055
Status
Address
University Hospitals Parma Medical Center
Parma, Ohio, 44129
Status
Address
Southern Ohio Medical Center
Portsmouth, Ohio, 45662
Status
Address
North Coast Cancer Care
Sandusky, Ohio, 44870
Status
Address
UH Seidman Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio, 44870
Status
Address
Cleveland Clinic Cancer Center Strongsville
Strongsville, Ohio, 44136
Status
Address
ProMedica Flower Hospital
Sylvania, Ohio, 43560
Status
Address
University of Toledo
Toledo, Ohio, 43614
Status
Address
South Pointe Hospital
Warrensville Heights, Ohio, 44122
Status
Address
Saint Ann's Hospital
Westerville, Ohio, 43081
Status
Address
Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, Ohio, 44691
Status
Address
Genesis Healthcare System Cancer Care Center
Zanesville, Ohio, 43701
Status
Address
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
Status
Address
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, 73120
Status
Address
Providence Portland Medical Center
Portland, Oregon, 97213
Status
Address
Kaiser Permanente Northwest
Portland, Oregon, 97227
Status
Address
Oregon Health and Science University
Portland, Oregon, 97239
Status
Address
Jefferson Abington Hospital
Abington, Pennsylvania, 19001
Status
Address
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, 18103
Status
Address
Saint Luke's University Hospital-Bethlehem Campus
Bethlehem, Pennsylvania, 18015
Status
Address
Geisinger Medical Center
Danville, Pennsylvania, 17822
Status
Address
Ephrata Cancer Center
Ephrata, Pennsylvania, 17522
Status
Address
Ephrata Community Hospital
Ephrata, Pennsylvania, 17522
Status
Address
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, 16505
Status
Address
Adams Cancer Center
Gettysburg, Pennsylvania, 17325
Status
Address
WellSpan Medical Oncology and Hematology
Hanover, Pennsylvania, 17331
Status
Address
Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania, 18201
Status
Address
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, 17033-0850
Status
Address
Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111
Status
Address
Allegheny General Hospital
Pittsburgh, Pennsylvania, 15212
Status
Address
West Penn Hospital
Pittsburgh, Pennsylvania, 15224
Status
Address
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232
Status
Address
Geisinger Cancer Services-Pottsville
Pottsville, Pennsylvania, 17901
Status
Address
Reading Hospital
West Reading, Pennsylvania, 19611
Status
Address
Wexford Health and Wellness Pavilion
Wexford, Pennsylvania, 15090
Status
Address
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, 18711
Status
Address
UPMC Susquehanna
Williamsport, Pennsylvania, 17701
Status
Address
WellSpan Health-York Cancer Center
York, Pennsylvania, 17403
Status
Address
WellSpan Health-York Hospital
York, Pennsylvania, 17403
Status
Address
Newport Hospital
Newport, Rhode Island, 02840
Status
Address
Rhode Island Hospital
Providence, Rhode Island, 02903
Status
Address
Miriam Hospital
Providence, Rhode Island, 02906
Status
Address
AnMed Health Cancer Center
Anderson, South Carolina, 29621
Status
Address
Roper Hospital
Charleston, South Carolina, 29401
Status
Address
Charleston Oncology - Roper
Charleston, South Carolina, 29403
Status
Address
Lowcountry Hematology Oncology PA-North Charleston
Charleston, South Carolina, 29406
Status
Address
Bon Secours Saint Francis Hospital
Charleston, South Carolina, 29414
Status
Address
Charleston Oncology - Saint Francis
Charleston, South Carolina, 29414
Status
Address
Lowcountry Hematology Oncology PA-West Ashley
Charleston, South Carolina, 29414
Status
Address
Saint Francis Cancer Center
Greenville, South Carolina, 29607
Status
Address
Lowcountry Hematology Oncology PA-Mount Pleasant
Mount Pleasant, South Carolina, 29464
Status
Address
Rapid City Regional Hospital
Rapid City, South Dakota, 57701
Status
Address
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, 57104
Status
Address
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134
Status
Address
The West Clinic - Wolf River
Germantown, Tennessee, 38138
Status
Address
The West Clinic - Mid-Town
Memphis, Tennessee, 38104
Status
Address
University of Tennessee Health Science Center
Memphis, Tennessee, 38163
Status
Address
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, 37232
Status
Address
Texas Oncology - Central Austin Cancer Center
Austin, Texas, 78731
Status
Address
Baylor University Medical Center
Dallas, Texas, 75246
Status
Address
M D Anderson Cancer Center
Houston, Texas, 77030
Status
Address
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork, Utah, 84003
Status
Address
Sandra L Maxwell Cancer Center
Cedar City, Utah, 84720
Status
Address
Logan Regional Hospital
Logan, Utah, 84321
Status
Address
Intermountain Medical Center
Murray, Utah, 84107
Status
Address
McKay-Dee Hospital Center
Ogden, Utah, 84403
Status
Address
Utah Valley Regional Medical Center
Provo, Utah, 84604
Status
Address
Saint George Regional Medical Center
Saint George, Utah, 84770
Status
Address
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah, 84106
Status
Address
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112
Status
Address
LDS Hospital
Salt Lake City, Utah, 84143
Status
Address
South Jordan Health Center
South Jordan, Utah, 84009
Status
Address
Central Vermont Medical Center/National Life Cancer Treatment
Berlin, Vermont, 05602
Status
Address
University of Vermont Medical Center
Burlington, Vermont, 05401
Status
Address
University of Vermont and State Agricultural College
Burlington, Vermont, 05405
Status
Address
Centra Alan B Pearson Regional Cancer Center
Lynchburg, Virginia, 24501
Status
Address
Virginia Cancer Institute
Richmond, Virginia, 23229
Status
Address
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298
Status
Address
VCU Community Memorial Health Center
South Hill, Virginia, 23970
Status
Address
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, 98520
Status
Address
Providence Regional Cancer System-Centralia
Centralia, Washington, 98531
Status
Address
Providence Regional Cancer Partnership
Everett, Washington, 98201
Status
Address
Providence Regional Cancer System-Lacey
Lacey, Washington, 98503
Status
Address
PeaceHealth Saint John Medical Center
Longview, Washington, 98632
Status
Address
Kaiser Permanente Washington
Seattle, Washington, 98112
Status
Address
Swedish Medical Center-First Hill
Seattle, Washington, 98122
Status
Address
Providence Regional Cancer System-Shelton
Shelton, Washington, 98584
Status
Address
PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664
Status
Address
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, 99362
Status
Address
Providence Regional Cancer System-Yelm
Yelm, Washington, 98597
Status
Address
United Hospital Center
Bridgeport, West Virginia, 26330
Status
Address
West Virginia University Charleston Division
Charleston, West Virginia, 25304
Status
Address
West Virginia University Healthcare
Morgantown, West Virginia, 26506
Status
Address
Camden Clark Medical Center
Parkersburg, West Virginia, 26101
Status
Address
Langlade Hospital and Cancer Center
Antigo, Wisconsin, 54409
Status
Address
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, 53105
Status
Address
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin, 54729
Status
Address
Marshfield Clinic Cancer Center at Sacred Heart
Eau Claire, Wisconsin, 54701
Status
Address
Saint Agnes Hospital/Agnesian Cancer Center
Fond Du Lac, Wisconsin, 54935
Status
Address
Aurora Health Center-Fond du Lac
Fond Du Lac, Wisconsin, 54937
Status
Address
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, 53022
Status
Address
Aurora Cancer Care-Grafton
Grafton, Wisconsin, 53024
Status
Address
Green Bay Oncology at Saint Vincent Hospital
Green Bay, Wisconsin, 54301-3526
Status
Address
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, 54301
Status
Address
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin, 54303
Status
Address
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311
Status
Address
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, 53142
Status
Address
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, 54601
Status
Address
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792
Status
Address
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, 54143
Status
Address
Bay Area Medical Center
Marinette, Wisconsin, 54143
Status
Address
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449
Status
Address
Froedtert Menomonee Falls Hospital
Menomonee Falls, Wisconsin, 53051
Status
Address
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, 53209
Status
Address
Ascension Southeast Wisconsin Hospital - Saint Joseph Campus
Milwaukee, Wisconsin, 53210
Status
Address
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215
Status
Address
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
Status
Address
Aurora Sinai Medical Center
Milwaukee, Wisconsin, 53233
Status
Address
Marshfield Medical Center - Minocqua
Minocqua, Wisconsin, 54548
Status
Address
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, 54017
Status
Address
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin, 54154
Status
Address
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904
Status
Address
Aurora Cancer Care-Racine
Racine, Wisconsin, 53406
Status
Address
Lakeview Medical Center-Marshfield Clinic
Rice Lake, Wisconsin, 54868
Status
Address
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, 54868
Status
Address
HSHS Saint Nicholas Hospital
Sheboygan, Wisconsin, 53081
Status
Address
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, 53081
Status
Address
Aspirus Cancer Care - Stevens Point
Stevens Point, Wisconsin, 54481
Status
Address
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin, 54235-1495
Status
Address
Aurora Medical Center in Summit
Summit, Wisconsin, 53066
Status
Address
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, 54241
Status
Address
Aspirus Regional Cancer Center
Wausau, Wisconsin, 54401
Status
Address
Marshfield Clinic-Wausau Center
Wausau, Wisconsin, 54401
Status
Address
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, 53226
Status
Address
Aurora West Allis Medical Center
West Allis, Wisconsin, 53227
Status
Address
Marshfield Medical Center - Weston
Weston, Wisconsin, 54476
Status
Address
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin, 54494
Status
Address
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, 54494
Status
Address
Big Horn Basin Cancer Center
Cody, Wyoming, 82414
Status
Address
Billings Clinic-Cody
Cody, Wyoming, 82414
Status
Address
Welch Cancer Center
Sheridan, Wyoming, 82801
International Sites
Status
Address
BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, V5Z 4E6
Status
Address
The Vitalite Health Network - Dr Leon Richard Oncology Centre
Moncton, New Brunswick, E1C 8X3
Status
Address
Royal Victoria Regional Health Centre
Barrie, Ontario, L4M 6M2
Status
Address
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2
Status
Address
Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7
Status
Address
Grand River Regional Cancer Centre at Grand River Hospital
Kitchener, Ontario, N2G 1G3
Status
Address
London Regional Cancer Program
London, Ontario, N6A 4L6
Status
Address
Trillium Health Partners - Credit Valley Hospital
Mississauga, Ontario, L5M 2N1
Status
Address
Lakeridge Health Oshawa
Oshawa, Ontario, L1G 2B9
Status
Address
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, K1H 8L6
Status
Address
Algoma District Cancer Program Sault Area Hospital
Sault Ste Marie, Ontario, P6B 0A8
Status
Address
Thunder Bay Regional Health Science Centre
Thunder Bay, Ontario, P7B 6V4
Status
Address
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5
Status
Address
University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9
Status
Address
Windsor Regional Cancer Centre
Windsor, Ontario, N8W 2X3
Status
Address
Hopital de la Cite-de-la-Sante
Laval, Quebec, H7M 3L9
Status
Address
The Research Institute of the McGill University Health Centre (MUHC)
Montreal, Quebec, H3H 2R9
Status
Address
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)
Quebec City, Quebec, G1R 2J6
Status
Address
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Sherbrooke, Quebec, J1H 5N4
Status
Address
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Status
Address
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4
Status
Address
Saint Vincent's University Hospital
Dublin, Co Dublin, 4
Status
Address
University College Hospital Galway
Galway, Co Galway,
Status
Address
University Hospital Waterford
Waterford, Co Waterford, 9
